Mechanical valve endocarditis caused by Gemella morbillorum

Al-Hujailan, Ghanem; Lagacé-Wiens, Philippe

doi:10.1099/jmm.0.47389-0

Cited by 23 publications

(37 citation statements)

References 15 publications

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“…Pre-existing damaged heart valves, poor dental hygiene, intravenous drug abuse, and extensive dental procedures have been reported as the main predisposing risk factors for endocarditis due to G.bergeriae. [9,19] To date, approximately 45 cases of endocarditis associated with Gemella spp. have been reported in the literature [5,7,8,12,20] and among them only 8 were caused by G.bergeriae, including 7 adult cases and 1 pediatric case.…”

Section: Discussionmentioning

confidence: 99%

Second Fatal Case of Infective Endocarditis caused by Gemella bergeriae

Ukudeeva¹,

Hawkins²,

Ahmad³

et al. 2017

Int J Biomed

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Section: Discussionmentioning

confidence: 99%

Second Fatal Case of Infective Endocarditis caused by Gemella bergeriae

Ukudeeva¹,

Hawkins²,

Ahmad³

et al. 2017

Int J Biomed

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“…Our literature review identified only four previous cases of G. morbillorum prosthetic valve endocarditis 3–6. Three of those patients were successfully treated with penicillin G for 6 weeks and gentamicin for 2 weeks3; ceftriaxone for 4 weeks and gentamicin for the first 2 weeks4; and with penicillin G plus rifampin for 6 weeks, gentamicin sulfate for the initial 2 weeks, and valve replacement, respectively 5. The fourth patient underwent valve replacement and was treated with vancomycin, gentamicin and rifampin; however, the patient died secondary to Escherichia coli bacteraemia during the postoperative period 6.…”

Section: Discussionmentioning

confidence: 99%

Gemella morbillorumprosthetic aortic valve endocarditis

Shahani¹

2014

BMJ Case Reports

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SUMMARYGemella morbillorum is facultative anaerobic, Gram-positive cocci and are a commensal part of human flora. The reported patient in this case, with a prosthetic bovine aortic valve, presented with fever, poor dental hygiene, new cardiac murmur and signs of congestive heart failure. Blood cultures were positive for a viridans streptococcal species; however, the organism could not be further identified at our institution. Echocardiogram demonstrated a decrease in ejection fraction and vegetation attached to the prosthetic aortic valve associated with a perivalvular abscess. The patient was treated with a 6-week regimen of penicillin G with gentamicin for the first 2 weeks along with cardiac surgery. The results from the 16S rRNA gene sequencing of the viridans streptococcal species were available, which reported the organism as G. morbillorum. This case adds to the literature on G. morbillorum prosthetic valve endocarditis and provides additional evidence to consider infectious endocarditis in the setting of G. morbillorum bacteraemia. BACKGROUND

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“…Although G. morbillorum possesses very low virulence comparing to some other pathogens, it was reported to cause endocarditis [4–7]. The morbidity of G. morbillorum endocarditis remains a rare occurrence so far.…”

Section: Introductionmentioning

confidence: 99%

Gemella morbillorum endocarditis of pulmonary valve:a case report

Zhu

Zheng

et al. 2017

J Cardiothorac Surg

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BackgroundPulmonary valve infective endocarditis is a rare finding for endocarditis. Infective endocarditis caused by Gemella morbillorum remains a scanty occurrence.Case presentationThis is a case reported of a 28-year-old Chinese male with endocarditis caused by pulmonary valve infection of Gemella morbillorum associated with congenital ventricular septal defect, atrial septal defect and double-chambered right ventricle. The patient presented with fever, shortness of breath, progressively worsening exertional fatigue, dyspnea and weight loss for 3 months. The diagnosis was made with transthoracic echocardiogram, blood cultures, and post-operative pathology. The patient developed congestive heart failure and was managed with aggressive antibiotic therapy followed by surgery. He underwent replacement of the pulmonary valve with an aortic bioprosthetic valve, repair of ventricular septal defect and atrial septal defect, reconstruction of the right ventricular outlflow tract, and excision of vegetations. His postoperative recovery was uneventful. No bacteria were isolated from the excised tissues. He was asymptomatic without recurrence at 3-month follow-up.ConclusionsThe rare pathogen such as Gemella morbillorum can be the cause of infective endocarditis and timely surgical repair is necessary if the infection is refractory or there is progression of congestive heart failure under antibiotic cover.

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Mechanical valve endocarditis caused by Gemella morbillorum

Cited by 23 publications

References 15 publications

Second Fatal Case of Infective Endocarditis caused by Gemella bergeriae

Second Fatal Case of Infective Endocarditis caused by Gemella bergeriae

Gemella morbillorumprosthetic aortic valve endocarditis

Gemella morbillorum endocarditis of pulmonary valve:a case report

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