Mechanical study of alisol B 23‐acetate on methionine and choline deficient diet‐induced nonalcoholic steatohepatitis based on untargeted metabolomics
Hua‐jun Li,
Yuan‐song Wang,
Ya‐nan Wang
et al.
Abstract:Alisol B 23‐acetate (AB23A) has been demonstrated to have beneficial effects on nonalcoholic steatohepatitis (NASH). However, the mechanisms of AB23A on NASH remain unclear. This study aimed to investigate the mechanisms underlying the metabolic regulatory effects of AB23A on NASH. We used AB23A to treat mice with NASH, which was induced by a methionine and choline deficient (MCD) diet. We initially investigated therapeutic effect and resistance to oxidation and inflammation of AB23A on NASH. Subsequently, we … Show more
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