Mechanical properties of elastomers for artificial leaflet heart valves

Parfeev, V. M.; Grushetskii, I. V.; Smurova, E. V.

doi:10.1007/bf00604034

Cited by 12 publications

(7 citation statements)

References 4 publications

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“…PHVs or mechanical heart valves fabricated from synthetic materials ( Table 1) have lifetime durability. However, patients Detmer et al, 1972;Gentle and Juden, 1984;Thornton et al, 1997 Polyurethane urea Jayabalan et al, 2000;Thomas et al, 2001;Thomas and Jayabalan, 2009 Polyurethane (PU) Mackay et al, 1996;Bernacca et al, 1997aBernacca et al, ,b, 2002bWheatley et al, 2000 Polyvinyl alcohol (PVA) Tadavarthy et al, 1975;Wan et al, 2002;Jiang et al, 2004;Millon and Wan, 2006 Silicone Carmen and Kahn, 1968;Carmen and Mutha, 1972;Cuddihy et al, 1976;Parfeev et al, 1983;Black, 1984 Titanium Mitamura et al, 1989;Jones et al, 2000;Aagaard, 2004;Leng et al, 2006;Guldner et al, 2011 Pyrolytic carbon Björk, 1972;Schoen et al, 1982;Goodman et al, 1996;Ritchie, 1996;Ely et al, 1998;Litzler et al, 2007 Polyether urethane (PEU) Boretos et al, 1975;Bernacca et al, 1995Bernacca et al, , 1997aWheatley et al, 2000 Polycarbonate urethane (PCU) Daebritz et al, 2004;Sachweh and Daebritz, 2006;<...>…”

Section: Application Of Biomaterials In Heart Valvesmentioning

confidence: 99%

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Biomaterials in Valvular Heart Diseases

Taghizadeh

Ghavami

Derakhshankhah

et al. 2020

Front. Bioeng. Biotechnol.

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Valvular heart disease (VHD) occurs as the result of valvular malfunction, which can greatly reduce patient’s quality of life and if left untreated may lead to death. Different treatment regiments are available for management of this defect, which can be helpful in reducing the symptoms. The global commitment to reduce VHD-related mortality rates has enhanced the need for new therapeutic approaches. During the past decade, development of innovative pharmacological and surgical approaches have dramatically improved the quality of life for VHD patients, yet the search for low cost, more effective, and less invasive approaches is ongoing. The gold standard approach for VHD management is to replace or repair the injured valvular tissue with natural or synthetic biomaterials. Application of these biomaterials for cardiac valve regeneration and repair holds a great promise for treatment of this type of heart disease. The focus of the present review is the current use of different types of biomaterials in treatment of valvular heart diseases.

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Section: Application Of Biomaterials In Heart Valvesmentioning

confidence: 99%

“…Nowadays, commonly used materials in PHVs include elastomers (mainly polyurethanes and silicones) (Parfeev et al, 1983), titanium (Phillips, 2001;Zhou et al, 2015), pyrolytic carbon (Cao, 1996;Ely et al, 1998;Phillips, 2001) and metal alloys (Akins, 1979;Buchanan, 2005; Table 1).…”

Section: Application Of Biomaterials In Heart Valvesmentioning

confidence: 99%

Biomaterials in Valvular Heart Diseases

Taghizadeh

Ghavami

Derakhshankhah

et al. 2020

Front. Bioeng. Biotechnol.

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“…One of the earliest polymers used in polymer heart valves was silicone rubber, but it fatigued easily under prolong and high bending stresses [7]. Polytetrafluoroethylene (PTFE) failed due to thrombosis and stiffening due to calcium deposits [8].…”

Section: Introductionmentioning

confidence: 99%

A Phospholipid-modified Polystyrene—Polyisobutylene— Polystyrene (SIBS) Triblock Polymer for Enhanced Hemocompatibility and Potential Use in Artificial Heart Valves

et al. 2008

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Poly(styrene-block-isobutylene-block-styrene) ('SIBS') is selected for a novel tri-leaflet heart valve due to its high resistance to oxidation, hydrolysis, and enzyme attack. SIBS is modified using six different phospholipids and its mechanical properties characterized by tensile stress, peel strength, shear strength, contact angle, and surface energy, and then for hemocompatibility by studying the adhesion of fluorescently labeled platelets in a parallel plate chamber under physiological flow conditions. Phospholipid modification decreases SIBS tensile stress (at 45% strain) by 30% and reduces platelet adhesion by a factor of 10, thereby improving its hemocompatibility and its potential use as a synthetic heart valve.

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“…One of the first materials used was silicone rubber, but it was unable to withstand repeated flexions associated with opening and closure (Chetta and Lloyd 1980;Parfeev, Grushetskii et al 1982). Polytetrafluoroethylene was also used as heart valve material, but it was not able to resist thrombosis and calcification (Imamura and Kaye 1977 Mechanical properties of polymers are dependant on the rate of application, temperature, and amount of strain.…”

Section: Synthetic Tri-leaflet Heart Valvesmentioning

confidence: 99%

Static and dynamic mechanical testing of a polymer with potential use as heart valve material

Aguirre¹

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DEDICATIONI dedicate this thesis to my Family and to Maria. Their love and support has been crucial in order for me to complete this work.iii ACKNOWLEDGMENTS Two and a half years ago I knocked on Dr. Schoephoerster's door. I told him I wanted to work towards a master's degree under his supervision. He told me he had nothing available at the time. Four more visits after that he had something for me. Dr.Schoephoerster, thank you for giving me a chance and believing in me.Maria Marquine, thank you for your love, hope, and understanding. Your help with the document was very important.Mariana Oliva, thank you for your long hours of work making the specimens for my tests.Siobhain Gallocher, thank you for always being there for me.Dr. Vladimir Kasyanov, I really enjoyed working with you. Thank you for your support.Dr. James Byrne, your help in the lab was very valuable.Valve Team, thank you for creating such an enjoyable work environment.Dr. Moore and Dr. Agarwal, thank you for your guidance and advice.Dr. Wu and his team, thank you for your help and patience. both its static and dynamic properties as compared to the PU. Hence, this composite has the potential to be a more suitable material for synthetic tri-leaflet heart valves.

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Mechanical properties of elastomers for artificial leaflet heart valves

Cited by 12 publications

References 4 publications

Biomaterials in Valvular Heart Diseases

Biomaterials in Valvular Heart Diseases

A Phospholipid-modified Polystyrene—Polyisobutylene— Polystyrene (SIBS) Triblock Polymer for Enhanced Hemocompatibility and Potential Use in Artificial Heart Valves

Static and dynamic mechanical testing of a polymer with potential use as heart valve material

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