Mechanical Properties of Chitin‐Based Nanocomposites

Thomas, Merin Sara; Pothan, Laly A.; Thomas, Sabu

doi:10.1002/9781118609958.ch6

Cited by 4 publications

(3 citation statements)

References 49 publications

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“…Developing effective delivery systems needed chemical modifications [ 86 ]. First, NPs based on CS derivatives can be chemically modified because of hydroxyl, acetamido, and amine functional groups [ [87] , [88] ]. Second, CS polymer conjugates/complexes, conjugation, or the addition of functional polymers in CS can mask CS weakness and achieve more efficient transfection [ 86 ].…”

Section: Chitosan-based Nanoparticlesmentioning

confidence: 99%

Drug release study of the chitosan-based nanoparticles

Herdiana

Wathoni

Shamsuddin

et al. 2022

Heliyon

200

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Recently, multifunctional drug delivery systems (DDSs) have been designed to provide a comprehensive approach with multiple functionalities, including diagnostic imaging, targeted drug delivery, and controlled drug release. Chitosan-based drug nanoparticles (CSNPs) systems are employed as diagnostic imaging and delivering the drug to particular targeted sites in a regulated manner. Drug release is an important factor in ensuring high reproducibility, stability, quality control of CSNPs, and scientific-based for developing CSNPs. Several factors influence drug release from CSNPs, including composition, composition ratio, ingredient interactions, and preparation methods. Early, CSNPs were used for improving drug solubility, stability, pharmacokinetics, and pharmacotherapeutics properties. Chitosan has been developed toward a multifunctional drug delivery system by exploring positively charged properties and modifiable functional groups. Various modifications to the polymer backbone, charge, or functional groups will undoubtedly affect the drug release from CSNPs. The drug release from CSNPs has a significant influence on its therapeutic actions. Our review's objective was to summarize and discuss the relationship between the modification in CSNPs as multifunctional delivery systems and drug release properties and kinetics of the drug release model. Kinetic models help describe the release rate, leading to increased efficiency, accuracy, the safety of the dose, optimizing the drug delivery device's design, evaluating the drug release rate, and improvement of patient compatibility. In conclusion, almost all CSNPs showed bi-phasic release, initial burst release drug in a particular time followed controlled manner release in achieving the expected release, stimuli external can be applied. CSNPs are a promising technique for multifunctional drug delivery systems.

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Section: Chitosan-based Nanoparticlesmentioning

confidence: 99%

Drug release study of the chitosan-based nanoparticles

Herdiana

Wathoni

Shamsuddin

et al. 2022

Heliyon

200

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“…The dyeing affinity (–Δμ°) is the difference of standard chemical potentials between the dye in the dyeing liquor and the dye on the fiber, and it represents the balance between the dye in the dyeing liquor and the dye on the fibers at a certain temperature. 21,29,30 The higher the chemical potential in the dyeing liquor, the greater the tendency of the dye to be absorbed by the fiber, which is like water flowing from a high place to a low place. It can be seen from Table 6 that the dyeing affinity values in the three media are positive ones, and the affinity values in the water bath dyeing are the smallest ones.…”

Section: Resultsmentioning

confidence: 99%

Thermodynamic properties of cotton dyeing with indigo dyes in non-aqueous media of liquid paraffin and D5

Fan

Shao

Miao

et al. 2021

Textile Research Journal

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On the basis of investigation into the dyeing equilibrium of cotton fibers with indigo dyes in decamethylcyclopentasiloxane (D5), liquid paraffin and water, the thermodynamic properties of cotton dyeing with indigo dyes in non-aqueous medium systems were studied in comparison with aqueous dyeing. The main works involved are as follows: firstly, the adsorption isotherms were created; then, the three theoretical adsorption models of Nernst, Langmuir and Freundlich were used to fit the adsorption isotherms created; finally, the thermodynamic parameters were calculated. The results showed that the adsorption isotherms were all in line with the Freundlich model. The order of dyeing affinity was in the sequence: liquid paraffin > D5 > water. The dyeing entropy in the three media showed positive values, which is mainly attributed to the adsorption of both indigo-leuco and water onto cotton fibers, thus reducing the ice-like structure formed among the water molecules in the dyeing system and the hydrophobic bonding structure formed among the non-aqueous medium molecules, then leading to an increase in the system disorder. The dyeing heat in the three media also showed positive values, due mainly to the absorption of thermal energy to “melt” the ice-like structure and to “break” the hydrophobic bonding structure. These dyeing thermodynamic properties are conducive to understanding and interpreting the dyeing performance and behavior of indigo dyes in non-aqueous dyeing systems.

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“…In the biomedical field, chitin and its derivatives are usually used for drug delivery, bone regeneration, blood cholesterol control, tissue engineering, wound healings and enzyme immobilization [132] , [133] , [134] , [135] , [136] . Given their wettability, mechanical stability, flexibility, optical clarity, transparency, gas permeability, and immunological compatibility, chitin and its derivatives are particularly well-suited for use in the production of contact lenses [137] , [138] .…”

Section: Chitin and Its Derivatives (Chitosan And Chitooligosaccharides)mentioning

confidence: 99%

Maximizing crustaceans (shrimp, crab, and lobster) by-products value for optimum valorization practices: A comparative review of their active ingredients, extraction, bioprocesses and applications

Zhang,

Ma,

Song

et al. 2024

Journal of Advanced Research

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Mechanical Properties of Chitin‐Based Nanocomposites

Cited by 4 publications

References 49 publications

Drug release study of the chitosan-based nanoparticles

Drug release study of the chitosan-based nanoparticles

Thermodynamic properties of cotton dyeing with indigo dyes in non-aqueous media of liquid paraffin and D5

Maximizing crustaceans (shrimp, crab, and lobster) by-products value for optimum valorization practices: A comparative review of their active ingredients, extraction, bioprocesses and applications

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