Mechanical properties of biocompatible protein polymer thin films

Buchko, Christopher J.; Slattery, Margaret J.; Kozloff, Kenneth M.; Martin, David C.

doi:10.1557/jmr.2000.0038

Cited by 36 publications

(18 citation statements)

References 19 publications

(16 reference statements)

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“…The bulk modulus of silicon is ∼170 GPa, whereas a value of ∼0.1 MPa for the modulus of human brain was obtained. 1 This corresponds to a 7-order of magnitude difference between the modulus of devices and brain tissue. This may lead to local strains at the sample surface during chronic implantations in living tissue that could enhance glial cell inflammation and thus reduce the biocompatibility of the device.…”

Section: Introductionmentioning

confidence: 99%

Impedance spectroscopy and nanoindentation of conducting poly(3,4-ethylenedioxythiophene) coatings on microfabricated neural prosthetic devices

Yang

Martin

2006

J. Mater. Res.

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The electrical and mechanical properties of conducting polymer poly(3,4-ethylenedioxythiophene) coatings on microfabricated neural probes have been evaluated by electrochemical impedance spectroscopy and nanoindentation techniques. Our results reveal that for poly(3,4-ethylenedioxythiophene) coatings, the minimum impedance correlates well with the mechanical properties. The lowest impedance films are also those that are the softest. This is consistent with microstructural observations by atomic force microscopy and scanning electron microscopy showing an increase in the effective surface area ("fuzziness") of the coatings. The presence of these conducting polymer coatings provides an intermediate step along the interface between the devices and brain tissue. This information provides clues for the design of strategies for improving the long-term performance of these electrodes in vivo.

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Section: Introductionmentioning

confidence: 99%

Impedance spectroscopy and nanoindentation of conducting poly(3,4-ethylenedioxythiophene) coatings on microfabricated neural prosthetic devices

Yang

Martin

2006

J. Mater. Res.

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“…report the diamond-PDMS adhesion energy to be 227 mJ/m 2 . However, from other sources the glass-PDMS adhesion energy is seen to lie in the range 12-150 mJ/m 2 [6, 26], and the diamond-PDMS adhesion energy is seen to lie in the range 20-500 mJ/m 2 [27-29]. …”

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confidence: 99%

Role of surface roughness in hysteresis during adhesive elastic contact

Kesari

Doll

Pruitt

et al. 2010

Philosophical Magazine Letters

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In experiments that involve contact with adhesion between two surfaces, as found in atomic force microscopy or nanoindentation, two distinct contact force (P) vs. indentation-depth (h) curves are often measured depending on whether the indenter moves towards or away from the sample. The origin of this hysteresis is not well understood and is often attributed to moisture, plasticity or viscoelasticity. Here we report experiments that show that hysteresis can exist in the absence of these effects, and that its magnitude depends on surface roughness. We develop a theoretical model in which the hysteresis appears as the result of a series of surface instabilities, in which the contact area grows or recedes by a finite amount. The model can be used to estimate material properties from contact experiments even when the measured P-h curves are not unique.

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“…The following constraints for the RGA method were set: (i) 0.07 a 0.98 13 ; (ii) W vdw W 500 mJ/m 2 . [40][41][42] Compared with the value of W vdw (i.e., 0.0178 mJ/m 2 ) obtained from the loading process, the adhesion energy created in the unloading process was much greater, indicating that the contribution of the van der Waals interactions could be disregarded. The obvious two-stage phenomenon attested the proposed mechanism of adhesion effects.…”

Section: Discussionmentioning

confidence: 89%

Modified method developed for contact-induced adhesion in indentation

Shen

Wei

Lin³

2009

J. Mater. Res.

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A modified method for contact-induced adhesion on the elastic deformation contact between a rigid spherical indenter and a polydimethylsiloxane (PDMS) specimen is proposed in the present study. Adhesion due to van der Waals interactions was found to be minimal during loading processes. During the unloading process, the experimental load-displacement data revealed two-stage phenomena. The successive advancing contacts between the specimen and the indenter were considered to induce interfacial adhesion and resulted in elastic tension outside the Hertzian contact radius. A real-coded genetic algorithm (RGA) was applied to evaluate how adhesion energy varied with penetration depth.

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Mechanical properties of biocompatible protein polymer thin films

Cited by 36 publications

References 19 publications

Impedance spectroscopy and nanoindentation of conducting poly(3,4-ethylenedioxythiophene) coatings on microfabricated neural prosthetic devices

Impedance spectroscopy and nanoindentation of conducting poly(3,4-ethylenedioxythiophene) coatings on microfabricated neural prosthetic devices

Role of surface roughness in hysteresis during adhesive elastic contact

Modified method developed for contact-induced adhesion in indentation

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