Mechanical Perspective on Increasing Brush Cytology Yield
Iyad Khamaysi,
Ronen Firman,
Patrick Martin
et al.
Abstract:Brush cytology is a sampling technique extensively used for mucosal surfaces, particularly to identify malignancies. A sample is obtained by rubbing the brush bristles over the stricture or lesion several times until cells are trapped. Brush cytology detection rate varies, with malignancy confirmed in 15−65% of cases of adenocarcinoma-associated biliary strictures and 44−80% of cases of cholangiocarcinoma. Despite the widespread use of brush cytology, there is no consensus to date defining the optimal biliary … Show more
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