Mechanical features of the duke biodegradable intravascular stent

Gammon, Roger S.; Chapman, Gregory D.; Agrawal, GM; Bauman, Robert P.; Phillips, Harry R.; Clark, Haydn; Stack, Richard S.

doi:10.1016/0735-1097(91)91907-v

Cited by 30 publications

(14 citation statements)

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“…One such biodegradable device, however, that warrants mention is the Duke Biodegradable Stent, which is made from a special form of poly-L-lactide capable of incorporating pharmacologically active agents. 161 Both selfexpanding and balloon-expandable versions of the Duke stent have been designed and tested in animals, 162 with promising results.…”

Section: Stent Coatingsmentioning

confidence: 99%

Frontiers in Interventional Cardiology

1998

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I n more than 20 years since the first percutaneous coronary revascularization procedures, the field of interventional cardiology has proliferated beyond all expectations. Now more than 1 million procedures are performed worldwide each year. Stenting has revolutionized the field, which previously relied on balloon dilatation in the majority of patients. With Ϸ50% of patients now undergoing stent implantation, the groundwork is laid for further important advances. In this article, we discuss the 4 most important new advances in the field of interventional cardiology: platelet inhibition, prevention of restenosis, stent evolution, and angiogenesis.

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Section: Stent Coatingsmentioning

confidence: 99%

Frontiers in Interventional Cardiology

1998

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“…Poly(lactide-co-glycolide) (PLGA) is a ductile aliphatic copolymer and has numerous pharmaceutical and biomedical applications including controlled release in drug delivery [2][3][4][5][6], scaffolds for wound dressing [7], cardiovascular or ureteric stents [8][9][10] and orthopedic fixtures [11]. Drug delivery is a promising and exciting application of PLGA because of its amorphous morphology [12].…”

Section: Introductionmentioning

confidence: 99%

Silver ion beam irradiation effects on poly(lactide-co-glycolide) (PLGA)/clay nanocomposites

2014

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Swift heavy ions induced modification of thin films of blends of poly(lactide-co-glycolide) (PLGA) (50:50) with organically modified nanoclay (Cloisite Ò 30B) has been studied, using optical, structural and surface morphological analysis. Presence of nanoclay is found to enhance the properties of this degradable copolymer by reducing the rate of degradation even at high irradiation fluence. Optical and structural analysis of the polymer nanocomposites suggests that both the cross-linking and chain scission phenomenon are caused by swift heavy ion irradiation. XRD measurements show intercalation of PLGA in the clay galleries. Surface morphology of a nanocomposite indicates significant changes after irradiation at various fluences.

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“…Stack et al21 were the first to introduce the concept of BPS made from poly( L ‐lactic acid) (PLLA). Their stent is self expanding and made up of braided PLLA fibres that maintain the requisite mechanical properties for up to 8 months in dog arteries 22. Despite preliminary in vivo studies suggesting minimal inflammatory and thrombotic reaction, as far as we know, further data remain sparse 23.…”

Section: Introductionmentioning

confidence: 99%

Chiral gas chromatography as a tool for investigations into illicitly manufactured methylamphetamine

et al. 2011

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The aim of this study was to develop a chiral gas chromatographic method for the separation of compounds likely to be found in the EMDE synthesis of methylamphetamine, a heavily abused stimulant drug. Here we describe the separation of the enantiomers of ephedrine, pseudoephedrine, chlorinated intermediates and methylamphetamine using fluorinated acid anhydrides as chemical derivatization reagents prior to gas chromatographic analysis on a 2,3-di-O-methyl-6-t-butyl silyl-β-cyclodextrin stationary phase (CHIRALDEX™ B-DM). Separation of the enantiomers of pseudoephedrine, methylamphetamine and chloro-intermediates was achieved using PFPA derivatization, and enantiomers of ephedrine using TFAA derivatization, in run times of less than 40 minutes. The use of HFBA as a derivatization reagent for this set of analytes is also discussed.

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Mechanical features of the duke biodegradable intravascular stent

Cited by 30 publications

References 0 publications

Frontiers in Interventional Cardiology

Frontiers in Interventional Cardiology

Silver ion beam irradiation effects on poly(lactide-co-glycolide) (PLGA)/clay nanocomposites

Chiral gas chromatography as a tool for investigations into illicitly manufactured methylamphetamine

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