Mechanical‐Enhanced and Durable Zwitterionic Hydrogel Coating for Inhibiting Coagulation and Reducing Bacterial Infection
Zhuojun Yan,
Mengmeng Yao,
Zhongming Zhao
et al.
Abstract:Blood‐contact medical devices are indispensable for clinical interventions, yet their susceptibility to thrombosis and bacterial infections poses substantial risks to treatment efficacy and patient well‐being. In this study, we introduce a polysulfobetaine/alginate‐CuII (SAC) zwitterionic hydrogel coating on polyurethane (PU) surfaces. This approach retained the superhydrophilic and antifouling nature of pSBMA while conferring the antibacterial effects of copper ions. Meanwhile, the copper alginate network int… Show more
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