Mechanical Complications of Takotsubo Cardiomyopathy: A Systematic Review

Arcay, Luis; López, José L.; Curry, Bryan

doi:10.1016/s0735-1097(22)01546-7

Cited by 1 publication

(2 citation statements)

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“…Mechanical complications also increase the mortality rate. The case-fatality rate for patients with mechanical complications is reported to be 63.6% from a study of 34 cases 60 . Other risk factors associated with higher fatality rates include male sex, lower systolic blood pressure and a history of diabetes mellitus 58,61 …”

Section: Cardiac Imagingmentioning

confidence: 99%

“…The case-fatality rate for patients with mechanical complications is reported to be 63.6% from a study of 34 cases. 60 Other risk factors associated with higher fatality rates include male sex, lower systolic blood pressure and a history of diabetes mellitus. 58,61 Future implications Owing to the uncertainty surrounding TTS pathophysiology, there is insufficient evidence on the management of acute episodes, prevention of significant cardiovascular complications and TTS recurrence, the most serious of which include free wall rupture of the ventricles and cardiac arrest.…”

Section: Prognosis and Complicationsmentioning

confidence: 99%

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An update on takotsubo syndrome

Alim,

Shah,

Zahera

et al. 2023

Journal of Cardiovascular Medicine

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Takotsubo syndrome (TTS) can be described as an acute, transiently occurring form of heart failure. It typically causes systolic dysfunction of the left ventricle (LV). Perhaps what is of most significance is the reversible nature of TTS, with many patients achieving recovery within a few weeks to months. TTS can be referred to by other names, attributed to its various precipitants, as well as the structural manifestations of the syndrome. Physical and emotional stressors have been identified as the most common of causes, hence the terms ‘stress cardiomyopathy’ and ‘broken heart syndrome’. Precipitants can range from psychological, and hormonal, to molecular mechanisms. The symptoms of TTS can coalesce with other conditions and hence give rise to many differential diagnoses. Most patients present with dyspnoea and chest pain. The latter also presents in acute coronary syndrome (ACS); thus, ACS is a common differential diagnosis for TTS. The coronavirus disease 2019 (COVID-19) pandemic saw a drastic increase in mental health concerns which have persisted beyond this period. Further studies into personality disorders and their potential predisposition to COVID-19 and thus TTS would advance our understanding of the neuropsychiatric triggers of TTS. There is also a need for a single sensitive and specific diagnostic test for TTS as its diagnosis relies on the culmination of clinical presentation, echocardiography, cardiac catheterization, and cardiovascular magnetic resonance imaging (CMR).

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Section: Cardiac Imagingmentioning

confidence: 99%