2013
DOI: 10.1093/eurheartj/eht248
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Mechanical circulatory support in cardiogenic shock

Abstract: Despite advances in coronary revascularization and widespread use of primary percutaneous interventions, cardiogenic shock complicating an acute ST-elevation myocardial infarction (CSMI) remains a clinical challenge with high mortality rates. Conservative management with catecholamines is associated with serious limitations, including arrhythmias, increased myocardial oxygen consumption, and inadequate circulatory support. Clinicians have therefore turned to mechanical means of circulatory support. Circulatory… Show more

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Cited by 387 publications
(288 citation statements)
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“…Mortality is high whatever the cause, and despite specific therapies targeted to the primary disorder (revascularisation, surgery, antiarrhythmics and immunosuppressants). So far, it is clear that this syndrome, with a stable mortality rate >40% as reported in most recent literature (1), requires a specific therapy. On top of medical therapy, mechanical circulatory support has emerged as the mainstay treatment for cardiogenic shock (1,2).…”
mentioning
confidence: 91%
“…Mortality is high whatever the cause, and despite specific therapies targeted to the primary disorder (revascularisation, surgery, antiarrhythmics and immunosuppressants). So far, it is clear that this syndrome, with a stable mortality rate >40% as reported in most recent literature (1), requires a specific therapy. On top of medical therapy, mechanical circulatory support has emerged as the mainstay treatment for cardiogenic shock (1,2).…”
mentioning
confidence: 91%
“…2,3 This technique is increasingly used as a short-term circulatory support in patients with RCF, providing a bridge to heart transplant. 4 Venoarterial extracorporeal membrane oxygenation may be used after heart transplant for conditions refractory to medical treatment like primary graft failure. 5 Previously, we reported our experience with patients who received VA-ECMO as a bridge to emergency heart transplant in the intensive care unit (ICU).…”
Section: Introductionmentioning
confidence: 99%
“…The advantages of ECMO over other percutaneous devices are its ease of insertion and its ability to support right, left, or biventricular failure at high blood flows. 3 This technique may be used as a bridge to heart transplant in both pediatric and adult patients. 2,4 Venoarterial extracorporeal membrane oxygenation is increasingly used as a short-term circulatory support in patients with RCF, providing a bridge to heart transplant.…”
Section: Introductionmentioning
confidence: 99%