Researches of the last years have allowed to establish that the laws of deformation and fracture of bulk ultrafine-grained (UFG) and coarse-grained (CG) materials are various both in static and in dynamic loading conditions. The influence of average grain size on the yield stress, the tensile strength, and the compression strength was established for metal alloys with a face-centered cubic (FCC), a body-centered cubic (BCC), and a hexagonal close-packed (HCP) structures. The study of the microstructure of the alloys after severe plastic deformation (SPD) by the electron backscatter diffraction (EBSD) technique showed the presence of a bimodal grain size distribution in the UFG alloys. Metal alloys with a bimodal grain size distribution possess a negative strain rate sensitivity of the yield stress and higher ductility at quasi-static strain rates. In this chapter, we will discuss the regularities of deformation at high strain rates, damage, and fracture of ultrafine-grained alloys.