Mechanical augmentation of the vertebral body by calcium phosphate cement injection

Ikeuchi, Masahiko; Yamamoto, Hiroshi; Shibata, Toshihiro; Ôtani, Midori

doi:10.1007/s007760170023

Cited by 49 publications

(31 citation statements)

References 11 publications

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“…For densities above 0.1 g/cm 3 , the mechanical augmentations were less dependent on bone density. These results agree closely with the in vitro vertebral augmentation study performed previously, 32,33 which also noted greater augmentation effect at lower initial bone mineral density. In addition, we observed that for PMMA volumes higher than 20%, the stiffening and strengthening effects were greater for the bipedicular approach versus posterolateral.…”

Section: Discussionsupporting

confidence: 94%

Biomechanics of Prophylactic Vertebral Reinforcement

Sun

Liebschner

2004

Spine

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Prophylactic vertebroplasty can be effective in reducing fracture risk. However, for the polymethyl methacrylate volume (20%) required for the successful reinforcement of high-risk vertebral bodies, the risk of complications will be as high as that for current vertebroplasty procedure for fracture repair. Therefore, alternative materials have to be investigated for prophylactic vertebroplasty. Furthermore, bipedicular vertebroplasty is the recommended approach due to its higher strengthening effect and easier surgical access than the posterolateral case.

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Section: Discussionsupporting

confidence: 94%

Biomechanics of Prophylactic Vertebral Reinforcement

Sun

Liebschner

2004

Spine

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“…Collectively they are known as preferential locations prone to fracture in the vertebral body [3,7,8,38]. This is the site where subsidence occurs with interbody fusion constructs in adjacent endplates [2,5,9,10,17,37].…”

Section: Introductionmentioning

confidence: 99%

The distribution of mineral density in the cervical vertebral endplates

2008

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Subsidence of various constructs into the vertebral body is a well-known complication in anterior fusion. Information on bone structure is needed, as a basis for improving these procedures. There are, however, no data available on the distribution of mineral density within vertebral endplates. In this study the regional distribution of mineralization within the cervical endplates with respect to endplate orientation (inferior and superior endplate) and level distribution (C3-C7) was examined by means of computed tomographic osteoabsorptiometry (CT-OAM). The distribution of mineralization in 80 cervical endplates of 8 spinal columns (4 male, 4 female, age range 38-62 years) in vertebrae C3-C7 was investigated by CT osteoabsorptiometry (CT-OAM). The subchondral mineralization distribution revealed considerable topographic differences within each endplate, whereby the areas of greatest density were found in the peripheral marginal zones with maxima in the posterolateral surface, whereas mineralization density was much lower in the central areas. The superior endplates showed an additional posteromedial maximum, whereas the inferior endplates showed an additional anterior mineralization maximum. Comparison of the distribution patters of inferior and superior endplates at different levels from C3 to C7 reveals a uniform increase of mineralization in the anterior portions from cranial to caudal. The mineralization distribution showed characteristic reproducible patterns. The maximal values occurred in the posterolateral parts, and can thus be considered a morphological substrate of high long-term loading. This can serve as a basis for improved prosthesis design and the anchorage point for various fusion techniques.

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“…Calcium phosphates are widely used in tissue engineering applications, most notably within orthopaedics [2][3][4][5]. Their biological properties, such as biocompatibility and biodegradability [6], has ensured their success as a bioceramic for adhesion applications, and warranted interest in these materials as potential substrates for inducing tissue growth.…”

Section: Introductionmentioning

confidence: 99%