Mechanical and Sensorimotor Implications With Ankle Osteoarthritis

Hubbard, Tricia J.; Hicks-Little, Charlie A.; Cordova, Mitchell L.

doi:10.1016/j.apmr.2008.11.020

Cited by 37 publications

(53 citation statements)

References 22 publications

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“…We know that recurrent ankle sprains are the second leading cause of posttraumatic ankle OA, and, as at the knee, 19,20 alterations in mechanical stability and neuromuscular control may contribute. 21 Tallroth et al 22 reported that 30 of 104 patients (29%) with knee OA also had ankle OA. They also observed that the greater the tilt at the ankle, the more degenerative changes in the knee, as damage to the ankle negatively affected the load on the knee, leading to greater amounts of knee-joint degeneration.…”

mentioning

confidence: 99%

Acute Ankle Sprain in a Mouse Model: Changes in Knee-Joint Space

Hubbard-Turner

Wikstrom

Guderian

et al. 2017

Journal of Athletic Training

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Context: Ankle sprains remain the most common orthopaedic injury. Conducting long-term studies in humans is difficult and costly, so the long-term consequences of an ankle sprain are not entirely known. Objective: To measure knee-joint space after a single surgically induced ankle sprain in mice. Design: Randomized controlled trial. Setting: University research laboratory. Patients or Other Participants: Thirty male mice (CBA/2J) were randomly placed into 1 of 3 surgical groups: the transected calcaneofibular ligament (CFL) group, the transected anterior talofibular ligament/CFL group, or a sham treatment group. The right ankle was operated on in all mice. Main Outcome Measure(s): Three days after surgery, all of the mice were individually housed in cages containing a solid-surface running wheel, and daily running-wheel measurements were recorded. Before surgery and every 6 weeks after surgery, a diagnostic ultrasound was used to measure medial and lateral knee-joint space in both hind limbs. Results: Right medial (P = .003), right lateral (P = .002), left medial (P = .03), and left lateral (P = .002) knee-joint spaces decreased across the life span. The mice in the anterior talofibular ligament/CFL group had decreased right medial (P = .004) joint space compared with the sham and CFL groups starting at 24 weeks of age and continuing throughout the life span. No differences occurred in contralateral knee-joint degeneration among any of the groups. Conclusions: Based on current data, mice that sustained a surgically induced severe ankle sprain developed greater joint degeneration in the ipsilateral knee. Knee degeneration could result from accommodation to the laxity of the ankle or biomechanical alterations secondary to ankle instability. A single surgically induced ankle sprain could significantly affect knee-joint function.

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mentioning

confidence: 99%

Acute Ankle Sprain in a Mouse Model: Changes in Knee-Joint Space

Hubbard-Turner

Wikstrom

Guderian

et al. 2017

Journal of Athletic Training

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“…Specifically, decreases in ankle muscle strength and increased mechanical stiffness have been observed relative to age matched controls. (Hubbard et al, 2009b) Laboratory-oriented evidence is also similar to the impairments associated with acute LAS and CAI. For example, static postural control (i.e.…”

Section: Post-traumatic Ankle Oamentioning

confidence: 64%

“…The vast majority of post-traumatic ankle OA research has been focused on patient-oriented evidence and the results consistently show, regardless of the scale used, that those with post-traumatic ankle OA have greater levels of self-reported disability relative to age matched controls. (Horisberger, Hintermann, & Valderrabano, 2009a;Hubbard, Hicks-Little, & Cordova, 2009b;Khazzam, Long, Marks, & Harris, 2006;Messenger, Anderson, & Wikstrom, 2011;Valderrabano et al, 2007;Valderrabano et al, 2006b) Clinical-oriented evidence shows similar impairments as those associated with acute LAS and CAI. Specifically, decreases in ankle muscle strength and increased mechanical stiffness have been observed relative to age matched controls.…”

Section: Post-traumatic Ankle Oamentioning

confidence: 97%

“…For example, static postural control (i.e. plantar pressure distributions and COP displacements) have been reported to be altered and/or increased (Horisberger et al, 2009a;Hubbard et al, 2009b;Messenger et al, 2011) and walking gait velocity, cadence, and stride length are all reduced in those with ankle OA. (Khazzam et al, 2006;Valderrabano et al, 2007) Most recently, Messenger et al (Messenger et al, 2011) illustrated that post-traumatic ankle OA alters gait initiation relative to uninjured age-matched controls.…”

Section: Post-traumatic Ankle Oamentioning

confidence: 99%

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Consequences of Ankle Inversion Trauma: A Novel Recognition and Treatment Paradigm

Hubbard¹,

Wikstrom²

2012

An International Perspective on Topics in Sports Medicine and Sports Injury

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“…Post-traumatic osteoarthritis is the most common form, accounting for more than 70% of all cases of osteoarthritis of the ankle. 1 Together with that, there are several reasons that make osteoarthritis of the ankle a different disease from osteoarthritis of the hip or knee: patients are generally younger and the weight-bearing articular surface is significantly smaller, causing greater pressure per unit of surface area; the ankle is surrounded by a fine layer of soft tissue, which can lead to serious complications in skin healing. 2 Lesions of the articular cartilage of the tibio-astragaline joint and secondary osteoarthritis of the ankle often cause pain, limited mobility, and functional disability.…”

Section: Introductionmentioning

confidence: 99%

Fresh bipolar osteochondral allograft of the ankle. Review of the literature and case report of a young patient with bilateral post-traumatic osteoarthritis

Pimenta

Carvalho

Amado

2012

Revista Española de Cirugía Ortopédica y Traumatología (English

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Objectives: The treatment of severe post-traumatic ankle arthritis remains a challenge nowadays. Since patients suffering from this pathology are mainly young and active people, a correct reconstruction, if possible, of the articular cartilage defects of the tibiotalar joint is very important to achieve a good result. Fresh bipolar osteochondral allograft (FBOA) is a promising operative technique, as an alternative to arthrodesis and total ankle replacement, in pain relief, restoration of function and indefinite delay of arthritic disease progression. Methods: The authors made a review of the literature and present a case report of a young 30-year-old man, with bilateral post-traumatic osteoarthritis of the ankle, treated with (FBOA). The patient was evaluated clinically and radiographically monthly. Results: Pain relief and postoperative function was significantly improved reaching 94 points in the left ankle (preoperative of 40 points), and 92 points in the right ankle (preoperative 42 points) AOFAS score. Conclusions: Fresh tibiotalar allografting seems to be a good alternative to arthrodesis and prosthetic replacement, in the treatment of ankle arthropathy and big articular cartilage defects mainly in young and active patients. This procedure achieves a good pain relief, maintaining functional joint motion and decreasing the risk of adjacent joint arthritis. © 2011 SECOT. Published by Elsevier España, S.L. All rights reserved. Aloinjerto osteocondral bipolar fresco del tobillo. Revisión de la literatura y presentación del caso de un paciente joven con artrosis bilateral postraumática ResumenObjetivo: El tratamiento de la artrosis postraumática grave del tobillo sigue siendo un reto en nuestros días. Dado que los pacientes afectos de esta afección son frecuentemente jóvenes y activos, la reconstrucción apropiada de los defectos articulares de la articulación tibioastragalina, si es posible, es muy importante para obtener un buen resultado. Los aloinjertos osteocondrales bipolares frescos (ABOF) constituyen una técnica quirúrgica prometedora, como una alternativa a la artrodesis o a la artroplastia de tobillo en cuanto al alivio de dolor, recuperación funcional y retraso de la progresión a la artrosis. Método: Se realiza una revisión de la literatura y se presenta el caso de un paciente varón de 30 años con artrosis bilateral postraumática del tobillo tratado con ABOF; el paciente fue revisado clínica y radiográficamente cada mes durante 15 meses.Resultados: Tanto el dolor como la función post-operatoria mejoraron de forma significativa, alcanzando 94 puntos en el tobillo izquierdo (puntuación preoperatoria de 40 puntos) y 92 puntos en el tobillo derecho (puntuación preoperatoria de 42 puntos).Conclusiones: El aloinjerto tibio-astragalino fresco parece ser una buena alternativa a la artrodesis o a la artroplastia en el tratamiento de la artropatía degenerativa del tobillo y de los defectos condrales articulares, principalmente en pacientes jóvenes y activos. Esta técnica consigue un buen alivio del dol...

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Mechanical and Sensorimotor Implications With Ankle Osteoarthritis

Cited by 37 publications

References 22 publications

Acute Ankle Sprain in a Mouse Model: Changes in Knee-Joint Space

Acute Ankle Sprain in a Mouse Model: Changes in Knee-Joint Space

Consequences of Ankle Inversion Trauma: A Novel Recognition and Treatment Paradigm

Fresh bipolar osteochondral allograft of the ankle. Review of the literature and case report of a young patient with bilateral post-traumatic osteoarthritis

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