Mechanical and histologic evaluation of Ca-P plasma-spray and magnetron sputter-coated implants in trabecular bone of the goat

Abstract

The aim of this study was to investigate the bone response to calcium phosphate (Ca-P) plasm a-spray and radiofrequency m agnetron sputter-coated im plants with comparable rough ness. Therefore, tapered conical screw designed im plants were installed in the trabecular bone of the femurs of nine goats. They were provided w ith two types of coatings, a plasm a-spray dual coating of fluorapatite and hydroxyapatite (FA/HA-PS) and a titanium plasm a-spray coating, cov ered w ith an am orphous Ca-P m agnetron sputtercoating (TPS/Ca-P-a). These implants were evaluated histologically and mechanically after 3 months of implantation. A wellcontrolled m ethod to apply and measure a torsional force to load die screw-type implants to the point of failure was introduced. All im plants healed uneventful and w ere well fixed. N o significant difference (Student t Lest, p > 0.05) for the torsional failure force w as m easured for both type of coatings. N evertheless, SEM revealed differently situated fracture planes. Light m icroscopy show ed intimate boneim plant contact for both types of coatings; original drill m ar gins w ere still visible. A lam ellar type of bone w ith some rem odeling lacunae w as show n. H istoniorphom etry re vealed a higher percentage of bone contact for the F A /H A -PS-coated im plants (student t test, p <0.05). M easurem ent of the am ount of bone revealed more bone mass around T PS/ C a-P-a-coated im plants (analysis of variance and Tukey m ultiple com parison, p < 0.05).

Calcium orthophosphate deposits: Preparation, properties and biomedical applications

“…However, to be objective, one must mention the studies, in which no positive effects have been detected [947,948]. Besides, the presence or absence of the positive effects might also depend on the deposition technique [932,949,950], as well as on the coating vendor [845]. Furthermore, an application or non-application of post-deposition treatments also influences the biological response of CaPO 4 deposits [951].…”

Bioceramics: Past, present and for the future

“…[56][57][58] However, further investigation of the sputtered CaP coatings is required to provide a better understanding of the likely long term clinical performance of these films.…”

Osteogenicity of titanium implants coated with calcium phosphate or collagen type-I in osteoporotic rats

“…Evidently, the negative impact of osteoporosis on osseointegration in the current rat model can be improved by using a thin CaP coating. This beneficial effect of RF magnetron sputtered CaP coatings on the osteogenicity of titanium implants was already described for noncompromised conditions in rabbits [36], goats [37,38], and dog mandible [39]. Also, the benefit of the use of CaP coated implants in general has already been observed in an estrogen-deficient osteoporotic rat model [40,41], rabbit model [42], sheep model [43,44] as well as dog model [45].…”