Meat intake and risk of diverticulitis among men

Cao, Yin; Strate, Lisa L.; Keeley, Brieze R.; Tam, Idy; Wu, Kana; Giovannucci, Edward; Chan, Andrew T.

doi:10.1136/gutjnl-2016-313082

Cited by 74 publications

(61 citation statements)

References 31 publications

(38 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Previous population-based studies have evaluated separately the association between various lifestyle factors and incidence of diverticulitis (8, 10–12, 14, 16, 17, 32). Evidence revealed that red meat intake, low dietary fiber intake, physical inactivity, obesity, and smoking, are associated with diverticulitis.…”

Section: Discussionmentioning

confidence: 99%

“…We have utilized these criteria in prior analyses, and documented the validity of self-reported diverticulitis in this population (6, 10, 11, 15, 29). …”

Section: Methodsmentioning

confidence: 99%

“…Previous research from our group and the United Kingdom have shown that dietary fiber is inversely associated with diverticular diseases (7–9). Beyond dietary fiber, red meat consumption has also been associated with diverticulitis risk (9, 10). Non-dietary lifestyle factors also played important roles.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Adherence to a Healthy Lifestyle is Associated With a Lower Risk of Diverticulitis among Men

Liu

Cao

Keeley

et al. 2017

American Journal of Gastroenterology

Self Cite

View full text Add to dashboard Cite

Objectives Diverticulitis is a common disease with high clinical burden. We evaluated the joint contribution of multiple lifestyle factors to risks of incident diverticulitis. We also estimated the proportion of diverticulitis preventable by lifestyle modifications. Methods We prospectively examined the association between lifestyle factors [red meat, dietary fiber intake, vigorous physical activity (activity with metabolic equivalent≥6), body mass index (BMI), and smoking] and risk of diverticulitis among participants in the Health Professionals Follow-Up Study. Results We documented 907 incident cases of diverticulitis during 757,791 person-years. High intake of red meat, low intake of dietary fiber, low vigorous physical activity, high BMI, and smoking were independently associated with increased risks of diverticulitis (all p<0.05). Low-risk lifestyle was defined as average red meat intake <51 grams/day, dietary fiber intake in the top 40% of the cohort (about 23 grams/day), vigorous physical activity in the highest 50% among participants with non-zero vigorous physical activity (roughly 2 hours of exercise weekly), normal BMI between 18.5–24.9 kg/m2, and never-smoker. There was an inverse linear relationship between number of low-risk lifestyle factors and diverticulitis incidence (p for trend<0.001). Compared to men with no low-risk lifestyle factors, the multivariable relative risks of diverticulitis were 0.71 [95% confidence interval (CI):0.59–0.87] for men with 1 low-risk lifestyle factor; 0.66 (95% CI:0.55–0.81) for 2 low-risk factors; 0.50 (95% CI:0.40–0.62) for 3 low-risk factors; 0.47 (95% CI:0.35–0.62) for 4 low-risk factors, and 0.27 (95% CI:0.15–0.48) for 5 low-risk factors. Adherence to a low-risk lifestyle could prevent 50% (95% CI:20–71%) of incident diverticulitis. Conclusions Adherence to a low-risk lifestyle is associated with reduced incidence of diverticulitis.

show abstract

Section: Discussionmentioning

confidence: 99%

“…We have utilized these criteria in prior analyses, and documented the validity of self-reported diverticulitis in this population (6, 10, 11, 15, 29). …”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Adherence to a Healthy Lifestyle is Associated With a Lower Risk of Diverticulitis among Men

Liu

Cao

Keeley

et al. 2017

American Journal of Gastroenterology

Self Cite

View full text Add to dashboard Cite

show abstract

“…In the multivariate analysis, the risk of P for trend = 0.03) than for processed red meat (defined as "bacon," "beef or pork hot dogs," "salami, bologna or other processed meat sandwiches," and "other processed red meats, such as sausage, kielbasa, etc") (TAbLE 2). 50 The reason for this finding is unknown, but it is hypothesized that microbial composition, diversity, and richness could be altered by this kind of diet.…”

Section: Fiber Intake and Occurrence Of Acute Diverticulitismentioning

confidence: 99%

“…A very recent prospective study assessed the association between the consumption of every type of meat (total red meat, red unprocessed meat, red processed meat, poultry, and fish) and the risk of incident acute diverticulitis. 50 The authors analyzed 46 461 men enrolled in the Health Professionals Follow -Up Study (from 1986 to 2012) and reported acute diverticulitis in 764 cases (1.64% of the population). Overall, red meat intake was associated with an increased risk of diverticulitis, but this risk increased only when the total red meat consumption was assessed.…”

Section: Fiber Intake and Occurrence Of Acute Diverticulitismentioning

confidence: 99%