Measuring the Ultrasonic Field Generated in Water upon the Deceleration of a Proton Beam

Albul, V. I.; Бычков, В. В.; Vasil'ev, S.S.; Gusev, K. E.; Demidov, V.S.; Demidova, É. V.; Krasnov, N. K.; Kurchanov, A. F.; Luk'yashin, V. E.; Sokolov, A. Yu.

doi:10.1023/b:inet.0000038397.71532.71

Cited by 11 publications

(16 citation statements)

References 2 publications

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“…Measurements were made from the point X = -15cm to ɏ = 17,9cm with step s 1 . The space-time picture of the radiation-acoustic field has been reproduced for the first time in papers [3,4] under the conditions close to the present experiment but only in parallel traces. In the present experiment the technique of space-time pattern reconstruction, developed in these papers is applied.…”

Section: Experiments and Simulationsupporting

confidence: 66%

“…The experiment was carried out at the external proton beam of ITEP accelerator in conditions similar to described in papers [2][3][4]. The acoustic field has been generated in water basin by the beam with energy 200 MeV.…”

Section: Experiments and Simulationmentioning

confidence: 99%

“…Simulations in accelerating laboratories use as a rule beam of lowenergy protons transverse to their stoppage. In this case the energy loss distribution has another shape: almost uniform along all range of protons comes to the end with a sharp maximum in a zone of so-called Bragg peak in the area of ionization range.In 2002 the space-time picture of acoustic field arising in water has been registered for the first time [2][3][4]. Measurements have been fulfilled in the points located on trajectories, parallel to beam direction.…”

Section: Introductionmentioning

confidence: 99%

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Experimental Study of the Acoustic Field Generated By Proton Beams in Water

Бычков¹,

Demidov²,

Demidova³

et al. 2008

AIP Conference Proceedings

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Section: Experiments and Simulationsupporting

confidence: 66%

Section: Experiments and Simulationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Experimental Study of the Acoustic Field Generated By Proton Beams in Water

Бычков¹,

Demidov²,

Demidova³

et al. 2008

AIP Conference Proceedings

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“…In addition to the aforementioned approaches, in vivo range/dose verification utilizing proton‐induced acoustic (protoacoustic) signals is a very promising alternative solution. Since the concept was initially proposed by Askaryan, many groups have worked on a number of aspects including both numerical simulations and experimental measurements . Sulak et al experimentally detected acoustic signals produced by proton beams in fluid media and successfully demonstrated a thermal expansion model for this phenomenon .…”

Section: Introductionmentioning

confidence: 99%

Simulation studies of time reversal‐based protoacoustic reconstruction for range and dose verification in proton therapy

Yu¹,

Li²,

Zhang³

et al. 2019

Medical Physics

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Purpose In vivo range verification in proton therapy is a critical step to help minimize range and dose uncertainty. We propose to employ a time reversal (TR)‐based approach using proton‐induced acoustics (protoacoustics) to reconstruct pressure/dose distribution in heterogeneous tissues. Methods The dose distribution of mono‐energetic proton pencil beam in a CT‐based patient phantom was calculated by Monte Carlo simulation. K‐wave toolbox was used to investigate protoacoustic pressurization, propagation and reconstruction in 2D. To address the tissue heterogeneity effect, a number of physical parameters, including mass density (ρ), speed of sound (c), volumetric thermal expansion coefficient (αV), isobaric specific heat capacity (Cp) and attenuation power law prefactor (α0), were empirically converted from CT number. The performance was evaluated using two figures of merit: mean square error (MSE) of pressure profiles and Bragg peak localization error (ΔBP). The impact of six parameters of the TR inversion was examined, including number of sensors, sampling duration, sampling timestep, spill time, noise level and number of iterations. Results The quantitative accuracy of TR reconstruction and its dependency on the selected parameters is presented. Under optimum conditions, the positioning accuracy of the Bragg peak can be controlled below 1 mm. For instance, MSE is 0.0123 and ΔBP is 0.59 mm under the following conditions (32 sensors, sampling duration: 600 µs, sampling timestep: 40 ns, spill time: 1 µs, no noise). Conclusions The feasibility of TR‐based protoacoustic reconstruction in 2D for proton range verification was first demonstrated. The approach is not only applicable to pencil beam, but also has potential to be extended to passive scattering systems.

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“…[6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21] Based on the difference between their characteristic proton spills, the protoacoustic pressure amplitude generated by single-bunch synchrotron spills (<1 µs) is expected to be higher than those generated by either clinical cyclotrons, which typically deliver proton spills with ∼50 µs rise and fall times, or clinical synchrotrons, which typically deliver with ∼200 µs rise and fall times. 22 Given the short (<1 µs) spill times and high (up to 100 mA instantaneous 11 ) proton current capabilities, previous observations of the protoacoustic signal have employed linear accelerator, 6 synchrotron, [7][8][9][10][11][12][13][14][15][16][17] and tandem-accelerator 18 proton sources. Protoacoustic signals have also been observed using cyclotron-derived proton beams, 6,19 but these have used custom, modifiable beam lines originally built for research before they were applied to clinical therapy use, and the spill rise times were not reported.…”

Section: Introductionmentioning

confidence: 99%

Experimental observation of acoustic emissions generated by a pulsed proton beam from a hospital‐based clinical cyclotron

et al. 2015

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Purpose: To measure the acoustic signal generated by a pulsed proton spill from a hospital-based clinical cyclotron. Methods: An electronic function generator modulated the IBA C230 isochronous cyclotron to create a pulsed proton beam. The acoustic emissions generated by the proton beam were measured in water using a hydrophone. The acoustic measurements were repeated with increasing proton current and increasing distance between detector and beam. Results: The cyclotron generated proton spills with rise times of 18 µs and a maximum measured instantaneous proton current of 790 nA. Acoustic emissions generated by the proton energy deposition were measured to be on the order of mPa. The origin of the acoustic wave was identified as the proton beam based on the correlation between acoustic emission arrival time and distance between the hydrophone and proton beam. The acoustic frequency spectrum peaked at 10 kHz, and the acoustic pressure amplitude increased monotonically with increasing proton current. Conclusions: The authors report the first observation of acoustic emissions generated by a proton beam from a hospital-based clinical cyclotron. When modulated by an electronic function generator, the cyclotron is capable of creating proton spills with fast rise times (18 µs) and high instantaneous currents (790 nA). Measurements of the proton-generated acoustic emissions in a clinical setting may provide a method for in vivo proton range verification and patient monitoring. C 2015 American Association of Physicists in Medicine. [http://dx

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Measuring the Ultrasonic Field Generated in Water upon the Deceleration of a Proton Beam

Cited by 11 publications

References 2 publications

Experimental Study of the Acoustic Field Generated By Proton Beams in Water

Experimental Study of the Acoustic Field Generated By Proton Beams in Water

Simulation studies of time reversal‐based protoacoustic reconstruction for range and dose verification in proton therapy

Experimental observation of acoustic emissions generated by a pulsed proton beam from a hospital‐based clinical cyclotron

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