Measuring environmental contamination in critical care using dilute hydrogen peroxide (DHP) technology: An observational cross-over study

Oon, Aileen; Reading, E; Ferguson, John; Dancer, S.J.; Mitchell, Brett G

doi:10.1016/j.idh.2019.12.005

Cited by 7 publications

(3 citation statements)

References 16 publications

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“…Vapor disinfection includes systems described as producing and dispersing vapors, aerosols, or droplets of disinfectants through spray, mist, or fogging machines. Hydrogen peroxide vapor was identified in 18% of studies [ 70 , 72 , 77 , 85 , 86 , 99 , 111 , 117 , 122 , 125 , 129 , 130 , 141 , 142 , 193 , 194 , 195 , 196 , 197 , 198 , 199 , 200 , 201 , 202 , 203 , 204 , 205 , 206 , 207 , 208 , 209 , 210 , 211 ]. Other vaporized disinfection methods, which included chlorine dioxide, sodium hypochlorite, essential oils, formalin, QACs, glutaral, beta propiolactone, steam, acidic electrolytic water, ozone, and steam, were identified in 10% of studies [ 70 , 84 , 137 , 203 , 212 , 213 , 214 , 215 , 216 , 217 , 218 , 219 , 220 , 221 , 222 , 223 ].…”

Section: Resultsmentioning

confidence: 99%

Evidence Map and Systematic Review of Disinfection Efficacy on Environmental Surfaces in Healthcare Facilities

Christenson¹,

Cronk

Atkinson³

et al. 2021

IJERPH

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Healthcare-associated infections (HAIs) contribute to patient morbidity and mortality with an estimated 1.7 million infections and 99,000 deaths costing USD $28–34 billion annually in the United States alone. There is little understanding as to if current environmental surface disinfection practices reduce pathogen load, and subsequently HAIs, in critical care settings. This evidence map includes a systematic review on the efficacy of disinfecting environmental surfaces in healthcare facilities. We screened 17,064 abstracts, 635 full texts, and included 181 articles for data extraction and study quality assessment. We reviewed ten disinfectant types and compared disinfectants with respect to study design, outcome organism, and fourteen indictors of study quality. We found important areas for improvement and gaps in the research related to study design, implementation, and analysis. Implementation of disinfection, a determinant of disinfection outcomes, was not measured in most studies and few studies assessed fungi or viruses. Assessing and comparing disinfection efficacy was impeded by study heterogeneity; however, we catalogued the outcomes and results for each disinfection type. We concluded that guidelines for disinfectant use are primarily based on laboratory data rather than a systematic review of in situ disinfection efficacy. It is critically important for practitioners and researchers to consider system-level efficacy and not just the efficacy of the disinfectant.

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Section: Resultsmentioning

confidence: 99%

Evidence Map and Systematic Review of Disinfection Efficacy on Environmental Surfaces in Healthcare Facilities

Christenson¹,

Cronk

Atkinson³

et al. 2021

IJERPH

View full text Add to dashboard Cite

show abstract

“…Dilute hydrogen peroxide (DHP) . This technique uses water vapor and oxygen in the ambient air to continuously produce ozone-free hydrogen peroxide [ 36 ]. The environmental hydrogen peroxide produced is 0.02 ppm that is well below human safety thresholds.…”

Section: Resultsmentioning

confidence: 99%

Environmental Disinfection of a Dental Clinic during the Covid-19 Pandemic: A Narrative Insight

Scarano

Inchingolo

Lorusso

2020

BioMed Research International

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Background. The control of biological hazard risk in health care and dental clinic environments represents a critical point in relation to the Covid-19 infection outbreak and international public health emergency. The purpose of the present review was to evaluate the scientific literature on the no-touch disinfection procedures in dental clinics aiming to limit transmission via airborne particles or fomites using no-touch procedures for environmental decontamination of dental clinics. Methods. An electronic database literature search was performed to retrieve research papers about Covid-19 and no-touch disinfection topics including full-length articles, editorials, commentaries, and outbreak studies. A total of 86 papers were retrieved by the electronic research. Results. No clinical article about the decontamination of a dental clinic during the Covid-19 pandemic was detected. About the topic of hospital decontamination, we found different no-touch disinfection procedures used in hospital against highly resistant organisms, but no data were found in the search for such procedures with respect to SARS-CoV-2: (1) aerosolized hydrogen peroxide, (2) H2O2 vapor, (3) ultraviolet C light, (4) pulsed xenon, and (5) gaseous ozone. One paper was retrieved concerning SARS-CoV-2; 32 documents focused on SARS and MERS. The cleaning and disinfection protocol of health care and dental clinic environment surfaces are essential elements of infection prevention programs, especially during the SARS-CoV-2 pandemic. Conclusion. The decontamination technique that best suits the needs of the dental clinic is peroxide and hypochlorous which can be sprayed via a device at high turbine speed with the ability of producing small aerosol particles, recommendable also for their low cost.

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“…During the use of DHP equipment, human presence was permitted, resulting in a 96.5% reduction in the average microbial load at the 5 hospitals on the first day of treatment. Another study conducted in an Australian hospital [35] examined disinfection in an intensive care unit using a device similar to DHP, referred to as dilute HP. The study’s findings revealed no significant differences in microbial reduction between the use of DHP disinfection and no disinfection.…”

Section: Improved Methods Of Cleaning and Disinfecting The Environmen...mentioning

confidence: 99%

Prevention and control of hospital-acquired infections with multidrug-resistant organism: A review

Ji,

2024

Medicine

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Multidrug-resistant is defined as nonsusceptibility to at least 1 agent in 3 or more antimicrobial categories. Controlling the spread of drug-resistant organisms is a key step in the management of hospital-acquired infections (HAIs). To review the progress of research on the prevention and control of HAIs with multidrug-resistant organism (MDRO) in the past 5 years, and to provide reference for the development of comprehensive measures for the prevention and control of HAIs with MDRO. We conducted a search in the PUBMED database for studies related to MDRO and HAIs from 2018 to 2023, then integrated this data with information sourced from the U.S.A. The Centers for Disease Control and Prevention. Utilizing information technology to monitor and provide feedback on hand hygiene practices can enhance compliance. Environmental disinfection techniques such as ultraviolet or hydrogen peroxide demonstrate potential in reducing MDRO transmission. While some studies support that contact isolation measures for MDRO-infected or colonized patients can reduce HAIs, others do not confirm this outcome. Approaches for MDRO colonization among patients or physicians may mitigate MDRO transmission risk. Implementing clusterization interventions proves to enhance efficiency and cost-effectiveness in preventing and controlling MDRO. Early screening for pathogen species emerges as a valuable strategy aiding in antimicrobial use control. Combined with evidence from the literature, implementing clusterization interventions that include measures such as monitoring and feedback on hand hygiene and improved environmental disinfection techniques can help prevent and control HAIs with MDRO. However, further clinical studies are needed to validate the optimal clusterization intervention.

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Measuring environmental contamination in critical care using dilute hydrogen peroxide (DHP) technology: An observational cross-over study

Cited by 7 publications

References 16 publications

Evidence Map and Systematic Review of Disinfection Efficacy on Environmental Surfaces in Healthcare Facilities

Evidence Map and Systematic Review of Disinfection Efficacy on Environmental Surfaces in Healthcare Facilities

Environmental Disinfection of a Dental Clinic during the Covid-19 Pandemic: A Narrative Insight

Prevention and control of hospital-acquired infections with multidrug-resistant organism: A review

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