Measuring cognitive complaints in breast cancer survivors: psychometric properties of the patient’s assessment of own functioning inventory

Dyk, Kathleen Van; Ganz, Patricia A.; Ercoli, Linda M.; Petersen, Laura; Crespi, Catherine M.

doi:10.1007/s00520-016-3352-6

Cited by 13 publications

(10 citation statements)

References 32 publications

(41 reference statements)

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“…Total score ranges from 0 to 165, with lower scores indicating better perceived cognitive functioning. The PAOFI has good reliability and validity for measuring perceived cognitive functioning in the cancer setting [ 46 , 47 ].…”

Section: Methodsmentioning

confidence: 99%

Computerized cognitive training in post-treatment hematological cancer survivors: a feasibility study

Mayo

Rourke

Atenafu

et al. 2021

Pilot Feasibility Stud

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Background Computerized cognitive training (CCT) programs have shown some effectiveness in alleviating cognitive symptoms in long-term cancer survivors. For patients presenting with cognitive symptoms in the early post-treatment phase, the benefit of CCT is unclear. To assess the possibility of testing the effectiveness of CCT in the early post-treatment period, our aim was to investigate the feasibility of an 8-week home-based, online CCT intervention among patients who have recently completed treatment for hematological malignancy. Methods This study was a single-arm, non-blinded, feasibility study. All participants were provided with the CCT intervention for an 8-week period. Feasibility was evaluated based on participant adherence and patient perceptions of the intervention, assessed through responses to an acceptability questionnaire and semi-structured interviews at the end of the intervention period. Results The feasibility study included 19 patients who had completed treatment for hematological malignancy at a Canadian tertiary cancer center. Adherence to the CCT intervention was limited, with only one participant meeting the criteria for intervention adherence. At the end of the intervention period, participants characterized the program as easy to follow (92%) and felt well-prepared for how to complete the exercises (100%). In semi-structured interviews, participants highlighted post-treatment barriers to intervention adherence that included symptom burden and competing time demands. Participants also suggested improvements to the intervention that could help maintain adherence despite these barriers, such as fostering a sense of accountability, providing personalized feedback and coaching, and enabling opportunities for peer support. Conclusions Participation in CCT can be challenging in the post-treatment period for hematological cancers. Further research on the effectiveness of CCT in this setting may require the implementation of strategies that support participants’ engagement with the intervention in the context of symptoms and competing demands, such as establishing a minimum dose requirement and integrating approaches to help promote and sustain motivation.

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Section: Methodsmentioning

confidence: 99%

Computerized cognitive training in post-treatment hematological cancer survivors: a feasibility study

Mayo

Rourke

Atenafu

et al. 2021

Pilot Feasibility Stud

View full text Add to dashboard Cite

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“…The PAOFI consists of four subscales that directly address cognitive functions: a Memory subscale, a Language and Communication subscale, a Motor/Sensory-Perceptual subscale and a Higher Level Cognitive and Intellectual Function (HLCF) subscale. A higher rating on any item indicated a lesser degree of impairment [32] .…”

Section: Methodsmentioning

confidence: 99%

Associations between patient-reported outcomes and radiation dose in patients treated with radiation therapy for primary brain tumours

Haldbo-Classen

Amidi

et al. 2021

Clinical and Translational Radiation Oncology

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“…Patient’s Assessment of Own Functional Inventory ( PAOFI ) assessed participants’ own perception of higher cerebral functions divided into four different domains; ‘memory’, ‘language’, ‘motor-perceptual functions’, and ‘higher cognitive functions’. Each question was scored on a Likert scale from 1 to 6, and cumulated scores for items with reference to each domain were calculated in accordance with Van Dyk et al [37] . For the correlation analysis of self-reported cognitive capacity and objectively measured cognitive functioning, the domain ‘Memory’ was tested against the outcomes ‘HVLT-delayed’, ‘HVLT-total’, and ‘WAIS-Digit span’.…”

Section: Methodsmentioning

confidence: 99%

Late toxicity in the brain after radiotherapy for sinonasal cancer: Neurocognitive functioning, MRI of the brain and quality of life

Sharma

Jensen

Amidi

et al. 2020

Clinical and Translational Radiation Oncology

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The aim of the study was to evaluate neurocognitive late effects, structural alterations and associations between cognitive impairment and radiation doses as well as cerebral tissue damage after radiotherapy for sinonasal cancer. Furthermore, the aim was to report quality of life (QoL) and self-reported cognitive capacity. Materials and methods: Recurrence-free patients previously treated with intensity-modulated radiotherapy with a curative intent were eligible for the study. Study examinations comprised comprehensive neurocognitive testing, MRI of the brain, and self-reported outcomes. Results: A total of 27 patients were included. Median age was 67 years (range 47-83). The majority of test outcomes were below normative values in any degree, and 37% of the participants had clinically significant neurocognitive impairment when compared with normative data. Correlations between absorbed doses to specific substructures of the brain and neurocognitive outcomes were present for Wechsler's Adult Intelligence Scale-digit span and Controlled Oral Word Association TestS. Structural MRI revealed macroscopic abnormalities in three patients; infarction (n = 1), diffuse white matter intensities (n = 2) and necrosis (n = 1). In the analysis of atrophy of cerebral tissue, no correlations were present with neither radiation dose to cerebral substructures nor neurocognitive impairment. The global QoL of the cohort was 75. The most affected outcomes were 'fatigue', 'insomnia', and 'drowsiness'. A total of 59% of participants reported significantly impaired quality of sleep. Self-reported cognitive function revealed that 'memory' was the most affected cognitive domain. For the domains of 'memory' and 'language', selfreported functioning was associated with objectively measured neurocognitive outcomes. Conclusion: Cerebral toxicity after radiotherapy for sinonasal cancer was substantial. Clinically significant cognitive impairment was present in more than one third of the participants, and several dose-response associations were present. Furthermore, the presence of macroscopic radiation sequelae indicated considerable impact of radiotherapy on brain tissue.

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Measuring cognitive complaints in breast cancer survivors: psychometric properties of the patient’s assessment of own functioning inventory

Cited by 13 publications

References 32 publications

Computerized cognitive training in post-treatment hematological cancer survivors: a feasibility study

Computerized cognitive training in post-treatment hematological cancer survivors: a feasibility study

Associations between patient-reported outcomes and radiation dose in patients treated with radiation therapy for primary brain tumours

Late toxicity in the brain after radiotherapy for sinonasal cancer: Neurocognitive functioning, MRI of the brain and quality of life

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