Measuring Brain Tissue Oxygenation Compared with Jugular Venous Oxygen Saturation for Monitoring Cerebral Oxygenation After Traumatic Brain Injury

Comparison Between Cerebral Tissue Oxygen Tension and Energy Metabolism in Experimental Subdural Hematoma

“…Yet, another explanation may be that reported PbtO 2 values often reflect a global level of oxygenation or CPP. Several authors have documented a close relation between the oxygen saturation of jugular venous blood (SjO 2 ) and PbtO 2 [10,40,41], and in the present study, we found a significant correlation between PbtO 2 and CPP in the ''bad-side'' (P = 0.02) during the acute phase after creation of the ASDH.…”

The Effect of Increased Inspired Fraction of Oxygen on Brain Tissue Oxygen Tension in Children with Severe Traumatic Brain Injury

“…The normal microvascular response to increased oxygen tension in the tissues is vasoconstriction [24,34]; however, experimental stroke studies demonstrate that this phenomenon may be absent or even reversed in injured or penumbral tissue [13,35]. A similar phenomenon also may explain different responses of PbO 2 to changes in PaCO 2 in injured versus noninjured tissue [36,37]. Therefore, the increased response of PbO 2 for a given change in PaO 2 in this study may reflect an alteration of normal tissue regulatory mechanisms, which may in turn be associated with poor outcome.…”

Jugular bulb desaturation during off-pump coronary artery bypass surgery

“…Monitoring of the jugular venous bulb oxygen saturation has been shown to be useful in a number of settings [12][13][14], but its routine use in elective OPCAB patients Our study is not the fi rst to investigate whether mixed venous oxygenation or other physiological variables could serve as suitable surrogates of alterations in cannot be justifi ed, due to its associated cost and invasiveness. Our study suggests that the intraoperative assessment of Sv O 2 and Pa CO 2 during routine OPCAB may offer useful information predicting trends in Sj O 2 while Sj O 2 itself is not directly monitored.…”

“…Sj O 2 is a useful monitor to evaluate global cerebral oxygen balance in patients following head injury [12][13][14][15] and during major cardiovascular procedures [10,16,17]. Jugular bulb desaturation (Sj O 2 ≤ 50%) is considered as a potential indicator of postoperative cognitive dysfunction (POCD) in conventional coronary artery bypass grafting (CABG) [10], but routine monitoring of Sj O 2 is invasive and expensive and may not be justifi ed to be performed in all elective OPCABs.…”