Measures of physiological stress: a transparent or opaque window into the status, management and conservation of species?

Dantzer, Ben; Fletcher, Quinn E.; Boonstra, Rudy; Sheriff, Michael J.

doi:10.1093/conphys/cou023

Cited by 360 publications

(423 citation statements)

References 161 publications

(285 reference statements)

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“…1). Second, caution must be exercised when interpreting the results of glucocorticoid assays (Lane 2006;Dantzer et al 2014). For example, high glucocorticoid values are not necessarily detrimental and low values beneficial, particularly if chronic stress leads to dysfunction of the HPA axis, rendering an animal unable to mount an appropriate stress response (Busch and Hayward 2009;Narayan and Hero 2014).…”

Section: Approaches To Understand the Relationship Between Stress Andmentioning

confidence: 99%

The relationship between physiological stress and wildlife disease: consequences for health and conservation

et al. 2016

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Wildlife populations are under increasing pressure from a variety of threatening processes, ranging from climate change to habitat loss, that can incite a physiological stress response. The stress response influences immune function, with potential consequences for patterns of infection and transmission of disease among and within wildlife, domesticated animals and humans. This is concerning because stress may exacerbate the impact of disease on species vulnerable to extinction, with consequences for biodiversity conservation globally. Furthermore, stress may shape the role of wildlife in the spread of emerging infectious diseases (EID) such as Hendra virus (HeV) and Ebola virus. However, we still have a limited understanding of the influence of physiological stress on infectious disease in wildlife.We highlight key reasons why an improved understanding of the relationship between stress and wildlife disease could benefit conservation, and animal and public health, and discuss approaches for future investigation. In particular, we recommend that increased attention be given to the influence of anthropogenic stressors including climate change, habitat loss and management interventions on disease dynamics in wildlife populations.Additional keyword: physiology.

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Section: Approaches To Understand the Relationship Between Stress Andmentioning

confidence: 99%

The relationship between physiological stress and wildlife disease: consequences for health and conservation

et al. 2016

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“…Concern about the non-lethal effects of human activities has resulted in the development of methods to quantify physiological and pathological responses of non-captive marine mammals (Ayres et al 2012, Rolland et al 2012, Hunt et al 2014a. In this regard, measurement of glucocorticoid hormones is the most widely applied approach to assess the physio logical impacts of anthropogenic factors in both marine and terrestrial wildlife, and is used as an indicator of the overall health of individuals and populations (Wikelski & Cooke 2006, Bonier et al 2009, Dickens & Romero 2013, Dantzer et al 2014.…”

Section: Introductionmentioning

confidence: 99%

“…Fecal sampling is non-invasive, providing a distinct advantage over methods requiring capture and handling, which elicit a stress response within minutes. Additionally, fGCs represent an integrative measure of the average level of circulating GCs (without diurnal or pulsatile fluctuations), making this sampling strategy ideal for evaluating chronic stress responses (Dickens & Romero 2013, Dantzer et al 2014). The temporal pattern of hormones in feces is determined primarily by gastrointestinal transit time for the species under study , Goymann 2012); in NARWs it has been estimated that fecal hormones reflect blood levels 1−2 d before sample collection (Rolland et al 2005).…”

Section: Introductionmentioning

confidence: 99%

Fecal glucocorticoids and anthropogenic injury and mortality in North Atlantic right whales Eubalaena glacialis

Rolland¹,

McLellan²,

Moore³

et al. 2017

Endang. Species. Res.

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“…Not only do these alternative sample types eliminate influences of capture stress, but they also integrate hormone secretion over longer time periods (hours to weeks) and may be preferable for studies of chronic and anthropogenic stress (Dantzer et al, 2014;Dickens and Romero, 2013).…”

Section: Introductionmentioning

confidence: 99%

Multi-year longitudinal profiles of cortisol and corticosterone recovered from baleen of North Atlantic right whales (Eubalaena glacialis)

Hunt

Lysiak

Moore

et al. 2017

General and Comparative Endocrinology

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Research into stress physiology of mysticete whales has been hampered by difficulty in obtaining repeated physiological samples from individuals over time. We investigated whether multi-year longitudinal records of glucocorticoids can be reconstructed from serial sampling along full-length baleen plates (representing ~10 years of baleen growth), using baleen recovered from two female North Atlantic right whales (Eubalaena glacialis) of known reproductive history. Cortisol and corticosterone were quantified with immunoassay of subsamples taken every 4 cm (representing ~60 d time intervals) along a full-length baleen plate from each female.In both whales, corticosterone was significantly elevated during known pregnancies (inferred from calf sightings and necropsy data) as compared to intercalving intervals; cortisol was significantly elevated during pregnancies in one female but not the other. Within intercalving intervals, corticosterone was significantly elevated during the first year (lactation year) and/or the second year (post-lactation year) as compared to later years of the intercalving interval, while cortisol showed more variable patterns. Cortisol occasionally showed brief high elevations ("spikes") not paralleled by corticosterone, suggesting that the two glucocorticoids might be differentially responsive to certain stressors. Generally, immunoreactive corticosterone was present in higher concentration in baleen than immunoreactive cortisol; corticosterone:cortisol ratio was usually >4 and was highly variable in both individuals. Further investigation of baleen cortisol and corticosterone profiles could prove fruitful for elucidating long-term, multi-year patterns in stress physiology of large whales, determined retrospectively from stranded or archived specimens. Hunt et al. -Baleen Hormones 3 HIGHLIGHTS• Immunoreactive cortisol and corticosterone are detectable in whale baleen• Single baleen plates contain multi-year longitudinal time series of glucocorticoids• Glucocorticoids tend to be elevated in baleen growth coincident with pregnancy• Corticosterone was present in baleen at much greater concentration than cortisol

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Measures of physiological stress: a transparent or opaque window into the status, management and conservation of species?

Cited by 360 publications

References 161 publications

The relationship between physiological stress and wildlife disease: consequences for health and conservation

The relationship between physiological stress and wildlife disease: consequences for health and conservation

Fecal glucocorticoids and anthropogenic injury and mortality in North Atlantic right whales Eubalaena glacialis

Multi-year longitudinal profiles of cortisol and corticosterone recovered from baleen of North Atlantic right whales (Eubalaena glacialis)

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