The production cross-section of 68 Ge, 69 Ge, 65 Zn and 67 Ga radioisotopes from alpha induced nuclear reaction with nat Zn have been measured using stacked foil activation technique followed by the off-line γ-ray spectroscopy in the incident alpha energy range 14.47-37 MeV. In this study we have presented cross-sections for nat Zn(α,x) 68 Ge, nat Zn(α,x) 69 Ge, nat Zn(α,x) 65 Zn and nat Zn(α,x) 67 Ga reactions. The obtained nuclear reaction cross-sections are compared with previous experimental data available in the EXFOR data library and theoretical results, calculated using TALYS nuclear reaction code. We have also performed the detailed uncertainty analysis for these nuclear reactions and their respective covariance metrics are presented. Since α-induced reactions are important in astrophysics, nuclear medicine, and improving the nuclear reaction codes so needful corrections related to the coincidence summing factor and the geometric factor have been considered during the data analysis in the present study.