Measurements of Elastic Moduli of Pharmaceutical Compacts: A New Methodology Using Double Compaction on a Compaction Simulator

On the Links Between Elastic Constants and Effective Elastic Behavior of Pharmaceutical Compacts: Importance of Poisson’s Ratio and Use of Bulk Modulus

“…In such a case, it would then be justified to consider only Young's modulus. Nevertheless, it was reported in a previous work that this approximation is not always justified …”

“…The values of Young's modulus and Poisson's ratio were obtained using double compaction experiments as described elsewhere . In this methodology, the first compaction is used to obtain the compact and the elastic properties are measured during the beginning of the second compaction.…”

Investigating the effect of tablet thickness and punch curvature on density distribution using finite elements method

“…The mechanical behavior of the powder was modeled using Drucker-Prager Cap (DPC) model. The parameters required to conduct the simulation were determined as already described in the literature (Brewin et al, 2008;Diarra et al, 2012;Han et al, 2008;Mazel et al, 2012). The values for the model parameters for MCC powder were those proposed by Diarra et al (2013).…”

Evolution of the Die-Wall Pressure during the Compression of Biconvex Tablets: Experimental Results and Comparison with FEM Simulation

“…The mechanical behavior of the powder was modeled using the Drucker–Prager Cap model. The parameters required to conduct the simulation were determined as already described in the literature . The friction angle β determined from uniaxial and diametrical compression tests did not vary much and had a magnitude of about 69°.…”