Measurement properties and responsiveness of the EQ-5D-Y-5L compared to the EQ-5D-Y-3L in children and adolescents receiving acute orthopaedic care

Verstraete, J; Marthinus, Zara; Dix-Peek, S; Scott, Des

doi:10.1186/s12955-022-01938-6

Cited by 13 publications

(10 citation statements)

References 39 publications

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“…Moreover, previous studies have indicated the low associations between EQ-5D-Y-3L dimension and PedsQL subscales scores in a cross-sectional fashion, such as in the pediatric orthopedic [27] and general population in Japan [25]. We found evident correlations (Spearman ρ > 0.3) between longitudinal changes in VAS of EQ-5D-Y and PedsQL for total score, emotional and social subscales (all Spearman ρ = 0.32, all p < 0.005), whereas no correlations (Spearman ρ < 0.3) appeared between each domain of EQ-5D-Y and PedsQL scores.…”

Section: Summary Of Ndingsmentioning

confidence: 97%

“…Alternatively, EQ-5D-Y was based on 3-level ordinal response choices, which may not be ideal for measuring changes in children's HRQOL. For instance, Verstraete et al indicated that EQ-5D-Y-5L can reduce the ceiling effect and had greater discriminate ability than EQ-5D-Y-3L on pain/discomfort and doing usual activity domains in the pediatric orthopedic population in South Africa [27].…”

Section: Summary Of Ndingsmentioning

confidence: 99%

“…For the psychometric evaluation, Verstraete et al have suggested that the VAS of EQ-5D-Y performed best in acutely-ill children to discriminate worst health status with the lowest VAS score of EQ-5D-Y than the total score of PedsQL in children and adolescents with acute health conditions in South Africa [27,28]. It is also worth mentioning that EQ-5D-Y refers to the "today" health state using a three-level ordinal scale, whereas the ve-point Likert scale in the PedsQL refers to the "past month", which might have an impact on the divergence validity of these HRQOL measures.…”

Section: Summary Of Ndingsmentioning

confidence: 99%

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Comparisons of EQ-5D-Y and PedsQL in pediatric patients with mild-to-moderate chronic kidney disease in longitudinal analyses

Hsu

Tain

et al. 2022

Preprint

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Objective: To characterize longitudinal changes and correlations between the measures of EQ-5D-Y and generic PedsQL and their associations with clinical changes in children and adolescents with mild-to-moderate chronic kidney disease (CKD). Methods: Participants were recruited from January 2017 to September 2021 in a medical center in Taiwan. Both instruments were administered in their initial visits and every 6-month subsequent visits. Spearman’s Rho (r) was used to assess correlations between the scores of EQ-5D-Y and PedsQL measures in longitudinal changes. Cohen’s effect size (ES) was used to evaluate the changes of scores/subscales over time. In addition, factors associated with longitudinal changes in the score/subscales were explored. Results: A total of 121 participants were enrolled, and 83 with ³3 HRQOL measures during the 3.5 years follow-up were assessed their changes of HRQOL measures. The correlations (r>0.3) appeared between the changes in the visual analog scale (VAS) of EQ-5D-Y and emotional and social subscales of PedsQL. ES was small (<0.5) in the VAS and level-sum-score (LSS) of EQ-5D-Y scores for the clinical changes in comorbidities, while some PedsQL subscales were medium to high (0.5–0.8 or >0.8). Hypertension, mineral bone disorder/anemia, and hyperuricemia associated with the changes in both HRQOL scores were varied by their various domains. Conclusion: Both EQ-5D-Y and PedsQL of HRQOL measures were responsive to worsened childhood CKD-related comorbidities during the follow-up; however, convergent validity between them was limited in some domains. The LSS of EQ-5D-Y showed greater changes than the VAS by comorbidity status; further comparison with utility weight is needed to determine the better performance of EQ-5D-Y.

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Section: Summary Of Ndingsmentioning

confidence: 97%

Section: Summary Of Ndingsmentioning

confidence: 99%

Section: Summary Of Ndingsmentioning

confidence: 99%

See 1 more Smart Citation

Comparisons of EQ-5D-Y and PedsQL in pediatric patients with mild-to-moderate chronic kidney disease in longitudinal analyses

Hsu

Tain

et al. 2022

Preprint

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“…The Kruskal–Wallis H test was computed for comparison of VAS scores between groups. It was expected that children with an orthopaedic condition and those with a functional disability would report more problems in the Mobility dimension compared to other groups [ 25 , 27 , 39 ]. It was also anticipated that children with an orthopaedic condition (being more acutely ill), would report more problems with Usual Activities and Pain or Discomfort [ 27 , 40 ].…”

Section: Instrumentsmentioning

confidence: 99%

The validity and reliability of the interviewer-administered EQ-5D-Y-3L version in young children

Amien

Scott

Verstraete

2023

Health Qual Life Outcomes

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Objectives The aim of this study was to determine the validity and reliability of the EQ-5D-Y-3L interviewer-administered (IA) version in South African children aged 5–7-years compared to 8–10-years. Methods Children aged 5–10-years (n = 388) were recruited from healthcare facilities, schools for learners with special educational needs and mainstream schools across four known condition groups: chronic respiratory illnesses, functional disabilities, orthopaedic conditions and the general population. All children completed the EQ-5D-Y-3L IA, Moods and Feelings Questionnaire (MFQ), Faces Pain Scale-Revised (FPS-R) and a functional independence measure (WeeFIM) was completed by the researcher. Cognitive debriefing was done after the EQ-5D-Y-3L IA to determine comprehensibility. Test–retest of the EQ-5D-Y-3L IA was done 48 h later and assessed using Cohen’s kappa (k). Results Results from children aged 5–7-years (n = 177) and 8–10-years (n = 211) were included. There were significantly higher reports of problems in the Looking After Myself dimension in the 5–7-year-olds (55%) compared to the 8–10-year-olds (28%) (x2 = 31.021; p = 0.000). The younger children took significantly longer to complete the measure (Mann-Whitney U = 8389.5, p < 0.001). Known-group validity was found at dimension level with children receiving orthopaedic management reporting more problems on physical dimensions across both age-groups. Convergent validity between Looking After Myself and WeeFIM items of self-care showed moderate to high correlations for both age-groups with a significantly higher correlation in the 8–10-year-olds for dressing upper (z = 2.24; p = 0.013) and lower body (z = 2.78; p = 0.003) and self-care total (z = 2.01; p = 0.022). There were fair to moderate levels of test-retest reliability across age-groups. Conclusion The EQ-5D-Y-3L IA showed acceptable convergent validity and test–retest reliability for measuring health in children aged 5–7-years. There was more report of problems with the dimension of Looking After Myself in the 5–7-year group due to younger children requiring help with dressing, including buttons and shoelaces due to their developmental age, rather than their physical capabilities. Therefore, it may be useful to include examples of age-appropriate dressing tasks. There was further some reported difficulty with thinking about the dimensions in the younger age-group, most notably for Usual Activities which includes a large number of examples. By decreasing the number of examples it may reduce the burden of recall for the younger age-group.

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“…An observational, analytical cohort study was conducted with the Y-5L, Y-3L, PedsQL and SRH question. A headto-head comparison of the Y-5L and Y-3L instrument performance is presented elsewhere [18,21].…”

Section: Study Design and Participantsmentioning

confidence: 99%

Comparison of the EQ-5D-Y-5L, EQ-5D-Y-3L and PedsQL in children and adolescents

Verstraete

Scott

2022

J Patient Rep Outcomes

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Background There is an increased use of Patient-Reported Outcome Measures (PROMs) in children and adolescents. The aim of this study was to compare the feasibility, concurrent validity and known-group validity of the EQ-5D-Y-3L (Y-3L), EQ-5D-Y-5L (Y-5L) and PedsQL self-report PROMs. Methods Five hundred and fifty children and adolescents, aged 8–15-years, with acute and chronic health conditions and a general population sample were recruited from schools and hospitals in Cape Town South Africa. All respondents self-completed the Y-5L, PedsQL, Self-Rated Health Question and Y-3L. Feasibility of the measures was determined by comparing the number of missing responses. Convergent validity was assessed by Spearman’s and Intra-class correlations on the corresponding items and summary scores respectively. Known-groups validity across health conditions was assessed across the summary scores of the measures with analysis of variance (ANOVA). Results The Y-3L and Y-5L had a total of 1% and 3.5% missing responses compared to 19% on the PedsQL. Similar items on the PedsQL and Y-3L/Y-5L showed high correlations (> 0.5) and related items showed moderate correlations (0.3). PedsQL total score was moderately and significantly associated with Y-3L and Y-5L level sum and VAS scores. The Y-3L and Y-5L level sum and VAS scores showed significant differences between known health groups whereas the PedsQL only showed differences between those with acute and chronic illness. Conclusion The results of this study show that the Y-3L and Y-5L showed comparable psychometric validity to the PedsQL. When considering the choice between the PedsQL, Y-5L and Y-3L these study results indicate that the EQ-5D-Y instruments (Y-3L and Y-5L) are recommended for studies assessing known-group validity or where missing data should be minimised. The PedsQL generic measure may be preferable in future studies including the general population where a ceiling effect is anticipated. When considering the choice between the Y-5L and the Y-3L there was no systematic difference in the validity between these instruments or between the Y-3L or Y-5L and the PedsQL. Thus, the selection of EQ-5D-Y measures to include in future studies should be guided by the characteristics of the population to be tested.

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Measurement properties and responsiveness of the EQ-5D-Y-5L compared to the EQ-5D-Y-3L in children and adolescents receiving acute orthopaedic care

Cited by 13 publications

References 39 publications

Comparisons of EQ-5D-Y and PedsQL in pediatric patients with mild-to-moderate chronic kidney disease in longitudinal analyses

Comparisons of EQ-5D-Y and PedsQL in pediatric patients with mild-to-moderate chronic kidney disease in longitudinal analyses

The validity and reliability of the interviewer-administered EQ-5D-Y-3L version in young children

Comparison of the EQ-5D-Y-5L, EQ-5D-Y-3L and PedsQL in children and adolescents

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