Wearable assistive devices are vitally important for tetraplegic individuals to provide valuable insights into their intended directives tailored to tongue motions in wireless healthcare industries. The flexible differentially driven extraoral antenna and rectenna measurement system are developed to enable differential sensing and monitoring of the set of unique tongue gestures for extraoral tongue drive system (eTDS) applications in three frequency bands of Industrial, Scientific, and Medical (ISM) (915.0 MHz, 2400 MHz, and 5800 MHz). The performance analysis is carried out using the heterogeneous human head model. The differential rectifier is coplanarly integrated with the differential extraoral antenna on the same 0.254 mm thin and 9.5 mm wider Rogers RT/ Duroid 6010 LM substrate. The footprint of the fabricated differential rectenna is 0.135
0.082
0.002
where the planar size of differential rectifier is 15.75
2.5 mm
2
. The fabricated systems are situated closely to an artificial head model. The maximum conversion efficiency achieved at 2400 MHz and 5800 MHz is 83.45% and 74.8%, respectively, for 11 dBm of RF input power. Further, the link analysis, including interfacing circuit losses, was carried out theoretically at 915 MHz. Thus, the proposed differential extraoral systems can be employed to acquire and transmit the user intentions in eTDS inspired healthcare applications.