Measurement of waist circumference for retrospective studies – Prospective validation of use of CT images to assess abdominal circumference

Ciudin, A.; Salvador, Rafael; Budoy, Alex; Ciudin, Andreea; Spinu, Cristina; Diaconu, M.G.; Constantin, Vlad Denis; Sánchez, Javier; Nicolau, Carlos; Alcaraz, Antonio

doi:10.1016/j.endonu.2013.10.004

Cited by 21 publications

(11 citation statements)

References 7 publications

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“…The following section describes the step‐by‐step process for using NIH ImageJ for estimation of WC and SM area. The use of abdominal circumference as an estimate for WC and techniques for tracing abdominal regions of interest (ROIs) for body composition analysis have been detailed and described for NIH ImageJ and other body composition medical imaging software 36 . ‐ 38 Similar methods will be implemented in this tutorial, modified specifically for use with NIH ImageJ for SM area assessment.…”

Section: Methodsmentioning

confidence: 99%

Measuring Abdominal Circumference and Skeletal Muscle From a Single Cross‐Sectional Computed Tomography Image

Gomez-Perez

Haus

Sheean

et al. 2015

J Parenter Enteral Nutr

210

116

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Diagnostic computed tomography (CT) scans provide numerous opportunities for body composition analysis including quantification of abdominal circumference, abdominal adipose tissues (subcutaneous, visceral and intermuscular) and skeletal muscle (SM). CT scans are commonly performed for diagnostic purposes in clinical settings and methods for estimating abdominal circumference and whole-body SM mass from them have been reported. A supine abdominal circumference is a valid measure of waist circumference (WC). The valid correlation between a single cross sectional CT image (slice) at third lumbar (L3) for abdominal SM and whole body SM is also well established. Sarcopenia refers to the age-associated decreased in muscle mass and function. A single dimensional definition of sarcopenia using CT images that includes only assessment of low whole body SM has been validated in clinical populations and significantly associated with negative outcomes. However, despite the availability and precision of SM data from CT scans and the relationship between these measurements and clinical outcomes, they have not become a routine component of clinical nutrition assessment. Lack of time, training, and expense are potential barriers that prevent clinicians from fully embracing this technique. This tutorial presents a systematic, step-by-step guide to quickly quantify abdominal circumference as a proxy for WC and SM using a cross-sectional CT image from a regional diagnostic CT scan for clinical identification of sarcopenia. Multiple software options are available, however this tutorial utilizes ImageJ, a free public domain software developed by the National Institutes of Health (NIH).

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Section: Methodsmentioning

confidence: 99%

Measuring Abdominal Circumference and Skeletal Muscle From a Single Cross‐Sectional Computed Tomography Image

Gomez-Perez

Haus

Sheean

et al. 2015

J Parenter Enteral Nutr

210

116

View full text Add to dashboard Cite

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“…Using previously described formulae, estimations were made of appendicular skeletal muscle indices (ASMI), total body fat mass and fat‐free mass. Waist circumference was measured from images using a recognised technique …”

Section: Methodsmentioning

confidence: 99%

Visceral adiposity predicts post‐operative Crohn's disease recurrence

Holt

Moore

Strauss

et al. 2017

Aliment Pharmacol Ther

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“…RRF pad distance was measured on the contra-lateral kidney at the level of the renal vein, as described [11]. Radiographic WC was utilized to measure WC at 1 cm above the umbilicus [12]. …”

Section: Methodsmentioning

confidence: 99%

Obesity as defined by waist circumference but not body mass index is associated with higher renal mass complexity

Bertrand

Thomas

Liu

et al. 2017

Urologic Oncology: Seminars and Original Investigations

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Objectives Obesity, typically defined as a body mass index (BMI) ≥ 30 kg/m2, is an established risk factor for renal cell carcinoma (RCC) but is paradoxically linked to less advanced disease at diagnosis and improved outcomes. However, BMI has inherent flaws, and alternate obesity-defining metrics that emphasize abdominal fat are available. We investigated three obesity-defining metrics, to better examine the associations of abdominal fat versus generalized obesity with renal tumor stage, grade, or R.E.N.A.L. nephrometry score. Methods and Materials In a prospective cohort of 99 subjects with renal masses undergoing resection and no evidence of metastatic disease, obesity was assessed using three metrics: body mass index (BMI), radiographic waist circumference (WC), and retro-renal fat (RRF) pad distance. R.E.N.A.L. nephrometry scores were calculated based on preoperative CT or MRI. Univariate and multivariate analyses were performed to identify associations between obesity metrics and nephrometry score, tumor grade, and tumor stage. Results In the 99 subjects, surgery was partial nephrectomy in 51and radical nephrectomy in 48. Pathology showed benign masses in 11 and RCC in 88 (of which 20 had stage T3 disease). WC was positively correlated with nephrometry score, even after controlling for age, sex, race, and diabetes status (p = 0.02); whereas BMI and RRF were not (p = 0.13, and p = 0.57, respectively). WC in stage T2/T3 subjects was higher than in subjects with benign masses (p= 0.03). In contrast, subjects with Fuhrman grade 1&2 tumors had higher BMI (p < 0.01) and WC (p = 0.04) than subjects with grade 3&4 tumors. Conclusions Our data suggest that obesity measured by WC, but not BMI or RRF, is associated with increased renal mass complexity. Tumor Fuhrman grade exhibited a different trend, with both high WC and BMI associated with lower grade tumors. Our findings indicate that WC and BMI are not interchangeable obesity metrics. Further evaluation of RCC-specific outcomes using WC versus BMI is warranted to better understand the complex relationship between general versus abdominal obesity and RCC characteristics.

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Measurement of waist circumference for retrospective studies – Prospective validation of use of CT images to assess abdominal circumference

Cited by 21 publications

References 7 publications

Measuring Abdominal Circumference and Skeletal Muscle From a Single Cross‐Sectional Computed Tomography Image

Measuring Abdominal Circumference and Skeletal Muscle From a Single Cross‐Sectional Computed Tomography Image

Visceral adiposity predicts post‐operative Crohn's disease recurrence

Obesity as defined by waist circumference but not body mass index is associated with higher renal mass complexity

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