Abstract:Recent work in humans with protein losing nephropathies has revealed increased urine concentrations of sulfated glycosaminoglycans (GAGs).Differences exist between normal patients, those with glomerulonephritis (GN), and those with amyloidosis thus potentially allowing differentiation without a renal biopsy. Aims of this study were to validate a simple spectrophotometric assay used to measure canine urinary GAGs, establish a n ormal reference range, and determine optimal storage conditions. Urine GAG concentra… Show more
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