MEASUREMENT OF TISSUE pH IN SKIN BY GLASS MICROELECTRODES

Meehan, StewartE.; Walker, W. F.

doi:10.1016/s0140-6736(79)90121-1

Cited by 9 publications

(2 citation statements)

References 3 publications

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“…For example, FILLER, et al [5,6] have implanted electrodes subfascially and originally coined the phrase "muscle surface pH" for their measurement. More recently, this pH measurement has been referred to äs tissue pH [11] or similarly tissue surface pH. The more precise and descriptive convention would be to state exactly where the measurement was made and therefore to refer to it äs "subfascial pH".…”

Section: Discussionmentioning

confidence: 99%

“…Low tissue surface pH in the absence of low blood pH has been observed in both adults and children suffering from occult blood loss [4,5,6,9,14,15] or peripheral vascular disease [11,12,13]. For this reason, it has been suggested that continuous measurement of tissue surface pH may be useful for monitoring metabolic acidosis resulting from reduced blood flow [13].…”

Section: Introductionmentioning

confidence: 99%

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Tissue surface pH monitoring during reduced blood flow: Metabolic implications and sources of error

Ef¹,

An²,

Pa³

1982

Journal of Perinatal Medicine

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Tissue surface pH monitoring during reduced blood flow: Metabolic implications and sources of error

Ef¹,

An²,

Pa³

1982

Journal of Perinatal Medicine

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Mussel‐Bioinspired Lignin Adhesive for Wearable Bioelectrodes

Hu,

Lu,

Cai

et al. 2024

Advanced Materials

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As a natural “binder,” lignin fixes cellulose in plants to foster growth and longevity. However, isolated lignin has a poor binding ability, which limits its biomedical applications. In this study, inspired by mussel adhesive proteins, acidic/basic amino acids (AAs) are introduced in alkali lignin (AL) to form ionic‐π/spatial correlation interactions, followed by demethylation to create catechol residues for enhanced adhesion activity. Atomic force microscopy reveals that catechol residues are the primary adhesion structures, with basic AAs exhibiting superior synergistic effects compared to acidic AAs. Demethylated lysine‐grafted AL exhibits the strongest adhesion force toward skin tissue. Molecular dynamic simulation and density functional theory calculations indicate that adhesion against skin tissue mainly results from hydrogen bonds and cation‐π interactions, with the adhesion mechanism being based on the Gibbs free energy of the Schiff base reaction. In summary, a biomimetic electrode based on lignin inspired by mussel adhesive proteins is prepared; the presented method offers a straightforward strategy for the development of biomimetic adhesives. Furthermore, this mussel‐inspired adhesive can be used as a wearable bioelectrode in biomedical applications.

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