Measurement of the number of lumbar spinal movements in the sagittal plane in a 24-hour period

Rohlmann, A.; Consmüller, Tobias; Dreischarf, Marcel; Bashkuev, Maxim; Disch, Alexander C.; Pries, Esther; Duda, Georg N.; Schmidt, Hendrik

doi:10.1007/s00586-014-3588-0

Cited by 37 publications

(15 citation statements)

References 21 publications

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“…This assumption is in agreement with Rohlmann et al (2014), who found that humans spend 20 to 25% of the entire day with the lumbar spine flexed. To investigate the role of annular fibres, the bone-remodelling simulation of the intact segment was run with and without fibres.…”

Section: Boundary and Loading Conditionssupporting

confidence: 92%

Numerical simulations of bone remodelling and formation following nucleotomy

Calvo-Echenique

Bashkuev

Reitmaier

et al. 2019

Journal of Biomechanics

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Nucleotomy is the gold standard treatment for disc herniation and has proven ability to restore stability by creating a bony bridge without any additional fixation. However, the evolution of mineral density in the extant and new bone after nucleotomy and fixation techniques has to date not been investigated in detail. The main goal of this study is to determine possible mechanisms that may trigger the bone remodelling and formation processes. With that purpose, a finite element model of the L4-L5 spinal segment was used. Bone mineral density (BMD), new tissue composition, and endplate deflection were determined as indicators of lumbar fusion. A bone-remodelling algorithm and a tissuehealing algorithm, both mechanically driven, were implemented to predict vertebral bone alterations and fusion patterns after nucleotomy, internal fixation, and anterior plate placement. When considering an intact disc height, neither nucleotomy nor internal fixation were able to provide the necessary stability to promote bony fusion. However, when 75% of the disc height was considered, bone fusion was predicted for both techniques. By contrast, an anterior plate allowed bone fusion at all disc heights. A 50% disc-height reduction led to osteophyte formation in all cases. Changes in the intervertebral disc tissue caused BMD alterations in the endplates. From this observations it can be drawn that fusion may be self-induced by controlling the mechanical stabilisation without the need of additional fixation. The amount of tissue to be removed to achieve this stabilisation remains to be determined.

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Section: Boundary and Loading Conditionssupporting

confidence: 92%

Numerical simulations of bone remodelling and formation following nucleotomy

Calvo-Echenique

Bashkuev

Reitmaier

et al. 2019

Journal of Biomechanics

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“…4c), which is considered as the most frequent everyday life activity, thus related to mechanical fatigue [29,30,34]. A more recent study, lead on a cohort of asymptomatic volunteers, revealed that flexion is the predominant range of movement of the spine during daily activities, therefore, preclinical evaluation tests on spinal implants should preferentially address a flexed condition [35]. A further confirmation on the higher loads reached in vivo for activities where the centre of mass of the upper body is moved anteriorly was also obtained using telemetrized VB-replacements [33].…”

Section: Discussionmentioning

confidence: 99%

Preclinical evaluation of posterior spine stabilization devices: can the current standards represent basic everyday life activities?

Barbera

Galbusera

Wilke³

et al. 2016

Eur Spine J

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“…Strengths and limitations of the study The use of three-vertebra specimens ensured that vertebral body compressive damage occurred naturally at a disc-bone interface, and so was not an artefact of the apparatus or dental plaster. Compressing the specimens while positioned in a flexed posture simulated typical physical activities in life (Dolan et al, 1994;Rohlmann et al, 2014) and the technique has been extensively validated (Chu et al, 2008Pollintine et al, 2004a) and shown to give reasonably accurate measures of the distribution of compressive loading on the vertebral body and neural arch. Specimens used in this study were from elderly humans, which ensured that the results are relevant to the population in which most osteoporotic vertebral deformities occur.…”

Section: Discussionmentioning

confidence: 99%

“…Vertebral fracture Each specimen was positioned in flexion (4 o to 10 o depending on flexibility) and compressed to failure at 3mm/s in order to simulate typical forward bending and lifting movements (Dolan et al, 1994), which are known to be common in life (Rohlmann et al, 2014). A loaddeformation graph was plotted in real time to allow the load to be removed at the first sign of damage, which was indicated by a reduction in gradient (stiffness).…”

Section: Stress Profilometry This Well-established (Mcnally Andmentioning

confidence: 99%

Vertebroplasty reduces progressive ׳creep’ deformity of fractured vertebrae

Luo

Pollintine

Annesley-Williams

et al. 2016

Journal of Biomechanics

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Elderly vertebrae frequently develop an "anterior wedge" deformity as a result of fracture and creep mechanisms. Injecting cement into a damaged vertebral body (vertebroplasty) is known to help restore its shape and stiffness. We now hypothesise that vertebroplasty is also effective in reducing subsequent creep deformations. Twenty-eight spine specimens, comprising three complete vertebrae and the intervening discs, were obtained from cadavers aged 67-92 years. Each specimen was subjected to increasingly-severe compressive loading until one of its vertebrae was fractured, and the damaged vertebral body was then treated by vertebroplasty. Before and after fracture, and again after vertebroplasty, each specimen was subjected to a static compressive force of 1kN for 1h while elastic and creep deformations were measured in the anterior, middle and posterior regions of each adjacent vertebral body cortex, using a 2D MacReflex optical tracking system. After fracture, creep in the anterior and central regions of the vertebral body cortex increased from an average 4513 and 885 microstrains, respectively, to 54,107 and 34,378 microstrains (both increases: P<0.001). Elastic strains increased by a comparable amount. Vertebroplasty reduced creep in the anterior and central cortex by 61% (P=0.006) and 66% (P=0.017) respectively. Elastic strains were reduced by less than half this amount. Results suggest that the beneficial effects of vertebroplasty on the vertebral body continue long after the post-operative radiographs. Injected cement not only helps to restore vertebral shape and elastic properties, but also reduces subsequent creep deformation of the damaged vertebra.

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Measurement of the number of lumbar spinal movements in the sagittal plane in a 24-hour period

Cited by 37 publications

References 21 publications

Numerical simulations of bone remodelling and formation following nucleotomy

Numerical simulations of bone remodelling and formation following nucleotomy

Preclinical evaluation of posterior spine stabilization devices: can the current standards represent basic everyday life activities?

Vertebroplasty reduces progressive ׳creep’ deformity of fractured vertebrae

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