Measurement of the local water content of an epoxy adhesive by fiber optic sensor based on Fresnel reflection

Grangeat, Romain; Girard, Marion; Lupi, Cyril; Leduc, Dominique; Jacquemin, Frédéric

doi:10.1016/j.ymssp.2019.106439

Cited by 8 publications

(7 citation statements)

References 17 publications

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“…A Fresnel reflection-based fiber sensor was applied for multipoint RI measurements using arrayed waveguide grating [ 15 ]. Fresnel reflection-based fiber RI sensors had also been used for in situ polymerization monitoring via RI measurement [ 16 , 17 ]. However, to our best knowledge, no Fresnel reflection-based fiber sensors have been applied for detecting biomolecules (e.g.…”

Section: Introductionmentioning

confidence: 99%

Development of a novel label-free all-fiber optofluidic biosensor based on Fresnel reflection and its applications

Zhuo

Song

et al. 2021

Analytica Chimica Acta

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A novel, compact, cost-effective, and robust label-free all-fiber optofluidic biosensor (LF-AOB) based on Fresnel reflection mechanism was built through integrating single-multi mode fiber coupler and highly sensitive micro-photodetector. The Fresnel reflection light intensity detected by the LF-AOB greatly depended on the RI change on the end-surface of the fiber probe according to experimental and simulation results. The capability of the LF-AOB for real-time in situ detection in optofluidic system were verified by measuring salt and protein solution, and the lowest limit of detection was 1.0 × 10 −6 RIU. Our proposed theory can effectively eliminate the influence of light intensity fluctuation, and one-point calibration method of sensor performance is conducive for rapid and convenient detection of targets. Label-free sensitive detection of SARS-Cov-2 Spike protein receptor-binding domain (S-RBD) and the binding kinetics assay between S-RBD and anti-S-RBD antibody were achieved using the LF-AOB. These contributed to the elegant design of all-fiber optical system with high efficiency, high resolution and sensitivity of micro-photodetector, and enhanced interaction between the light and the samples at the liquid-sensor interface because of the large surface area of the multi-mode fiber probe. The LF-AOB can be extended as a universal sensing platform to measure other factors associated with refractive index because its high sensitivity, low sample consumption (∼160 nL), and capability of real-time in situ detection.

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Section: Introductionmentioning

confidence: 99%

Development of a novel label-free all-fiber optofluidic biosensor based on Fresnel reflection and its applications

Zhuo

Song

et al. 2021

Analytica Chimica Acta

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“…These outcomes suggest that the addition of the virus increased the refractive index and caused a red shift from 630 nm to 634 nm. Furthermore, the red shift increased as there was an increase in viral concentrations, which is attributed to a further change in the refractive index 9 . With the undiluted virus exhibiting signs of having the highest refractive index, followed by sample 1 and sample 2 having the lowest.…”

Section: Transmission Spectroscopy and Sem Analysismentioning

confidence: 96%

Quantification of viral particles using a photonic crystal biosensor

Lugongolo,

Ombinda-Lemboumba,

Maphanga

et al. 2024

Plasmonics in Biology and Medicine XXI

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The quantification of human immunodeficiency virus at point of care remains a challenge in resource limited settings. The incorporation of nanotechnology and label free optical biosensing has unlocked promising opportunities in the development of diagnostic tools for infectious diseases. Optical biosensors offer a rapid and sensitive optical method for various biological materials such as cells, biomolecules, and viruses by monitoring the dielectric permittivity changes at the interface of a transducer substrate and the analyte. This work focuses on exploring photonic crystal biosensor efficiency and sensitivity for viral load measurement. Photonic crystal biosensors are a unique class of biosensors that allow for label free analysis as they can control and confine light propagation due to the photonic bandgap. Silane treated photonic crystal was functionalized with anti-HIV-gp120 antibody before the addition of various concentrations of HIV pseudovirus. The samples were analyzed on a custom build transmission spectroscopy that used white light as a light source. The results showed a red shift at different virus concentrations, which demonstrates that photonic crystal biosensors are sensitive enough to detect differences in virus concentrations. Therefore, photonic crystals have a potential in the development of photonic crystal-based biosensors for viral load detection.

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“…This sensor, called a Fresnel sensor, allows to measure locally the index of refraction of a material, the measurement being carried out at the end of the optical fiber. It was shown in a previous study the possibility of measuring the local water content without calibration in an adhesive epoxy [14]. For this purpose, a model was used to relate the local refractive index to the local water content.…”

Section: Fiber Optic Measurementsmentioning

confidence: 99%

Local water content field within an epoxy/metal bonded assembly in immersion

Grangeat

Girard

Lupi

et al. 2022

The Journal of Adhesion

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HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L'archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d'enseignement et de recherche français ou étrangers, des laboratoires publics ou privés.

show abstract

Measurement of the local water content of an epoxy adhesive by fiber optic sensor based on Fresnel reflection

Cited by 8 publications

References 17 publications

Development of a novel label-free all-fiber optofluidic biosensor based on Fresnel reflection and its applications

Development of a novel label-free all-fiber optofluidic biosensor based on Fresnel reflection and its applications

Quantification of viral particles using a photonic crystal biosensor

Local water content field within an epoxy/metal bonded assembly in immersion

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