Measurement of swirling flow in a blood chamber by laser Doppler imaging system

Abstract

We developed a flow visualization system based on laser Doppler velocimetry (LDV) to investigate the relationship between blood flow and blood coagulation in a blood chamber in an extracorporeal circulation circuit. Linear laser intersection was used to implement 32-point simultaneous measurement. The intersection region was traversed along the axial direction to obtain a two-dimensional (2D) velocity distribution as a contour graph. The optical assembly of the flow visualization system is very simple. Furthermore, there is no need to submerge the measurement object in a square water tank to reduce the influence of refraction and reflection. Because LDV has inherently high measurement accuracy, even slight flow velocity changes (less than 1 mm s −1 ) can be clearly identified in a blood chamber.

Research progress and clinical application of laser Doppler blood flow measurement technology

“…In 2015, KYODEN and et al [24] proposed a cross-sectional multi-point laser Doppler velocimetry system, employing a linear multi-channel measurement approach to achieve the measurement of transient 2D blood flow velocity, and obtaining transient 2D velocity distribution. In 2020, Hiroki Ishida et al [25] developed a laser Doppler-based blood flow visualization system, utilizing linear laser intersection to achieve simultaneous measurement at 32 points. This system can be used to study the relationship between blood flow and blood coagulation in the blood cavity of extracorporeal circulation circuits.…”

Current State of Knowledge in Ocular Blood Flow in Glaucoma: A Narrative Review

“… 45 LDV without ionizing radiation is a useful approach for diagnosing and monitoring glaucoma patients. 46 …”