Measurement of stray neutron doses inside the treatment room from a proton pencil beam scanning system

Mojżeszek, Natalia; Farah, Jad; Kłodowska, Magdalena; Ploc, Ondřej; Stolarczyk, Liliana; Waligórski, M.P.R.; Olko, P.

doi:10.1016/j.ejmp.2017.01.013

Cited by 22 publications

(19 citation statements)

References 25 publications

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“…10 One concern of using an MLC system for beam shaping in proton therapy is the enhancement of the neutron production. 15,[19][20][21] In this simulation, the MLC system is used to replace the static aperture to shape the double-scattering proton beam to produce conformal dose for the PTV. It is not used to modulate intensity of the beam as in photon beams.…”

Section: Discussionmentioning

confidence: 99%

Simulation study of proton arc therapy with the compact single-room MEVION-S250 proton therapy system

2020

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Aim: The purpose of this study is to investigate the feasibility of proton arc therapy (PAT) using the double-scattering MEVION-S250 proton system. The treatment planning and dose delivery parameters from PAT were compared with conventional treatment planning techniques. Materials and methods: PAT was simulated with multiple conformal and fixed-aperture beams (5–15) using the MEVION-S250-double-scattering proton system. Conformal apertures were simulated with the Eclipse-treatment-planning system: (a) using a static single aperture that provides the best average conformal circular or rectangular apertures to cover the tumour from different angular views (SPAT), and (b) dynamic conformal apertures of the tumour shape at each irradiation angle that can be obtained from a multi-leaf-collimator system (DPAT). Results: The DPAT and SPAT plans provided superior dose coverage and sparing of normal tissues in comparison with conventional plans (CPT). The entrance normal tissue and skin doses (<40%) were lowered significantly by delivering dose from different directions over a wider angular view compared to conventional plans that have large entrance dose from only two fields. While the mean and minimum doses from PAT and CPT were comparable, the maximum doses from arc plans were lower than the maximum doses in conventional plans. The SPAT and DPAT plans had comparable dose parameters for regularly shaped targets. The heterogeneity index (HI) was superior in PAT plans which improved with increasing number of beams in arc plans for the different treatment sites. The conformality index (CI) depends on the treatment site and complexity of the shape of the planning target volume where for brain, pancreatic and lung tumours, PAT plans conformality was comparable and sometimes superior to CPT; and HI and CI were generally better in DPAT compared to SPAT. Conclusions: PAT plans have superior dose coverage and sparing of normal tissues compared to CPT plans using the MEVION double-scattering system as shown in this simulation study. Ideally, conformal proton arcs require beam shaping and dose delivery with the gantry moving; however, the MEVION double-scattering system lacks a multi-leaf collimator system and cannot deliver dose during gantry rotation. The single aperture conformal proton therapy technique is more time and cost effective compared with conventional techniques that are used currently with the MEVION proton therapy system because of the elimination of the need for patient-specific compensators. In present study, PAT was simulated with the MEVION double-scattering proton therapy system; however, it can be performed also with other proton therapy systems.

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Section: Discussionmentioning

confidence: 99%

Simulation study of proton arc therapy with the compact single-room MEVION-S250 proton therapy system

2020

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“…All detectors were located 1.25 m above the floor and aligned with the horizontal plane. The selected setup is similar to previous EURADOS WG9 experiments (Farah et al 2015, Mojżeszek et al 2017. Active measurements were performed in parallel with the exposure of passive detectors.…”

Section: Methodsmentioning

confidence: 99%

Out-of-field doses for scanning proton radiotherapy of shallowly located paediatric tumours—a comparison of range shifter and 3D printed compensator

et al. 2021

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“…H*(10) values decreased significantly with distance and angular position with respect to the beam axis. The influence of proton beam parameters on the secondary radiation doses was investigated in a separate experimental campaign using active detectors positioned around 300 × 300 × 600 mm 3 solid water phantom (Mojżeszek et al 2017). The dependence of H*(10) on proton beam energies between 100 and 220 MeV, field sizes from 2 × 2 to 20 × 20 cm 2 and modulation widths from 0 to 15 cm was verified.…”

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confidence: 99%

The European radiation dosimetry group – Review of recent scientific achievements

Rühm

Ainsbury

Breustedt

et al. 2020

Radiation Physics and Chemistry

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Measurement of stray neutron doses inside the treatment room from a proton pencil beam scanning system

Cited by 22 publications

References 25 publications

Simulation study of proton arc therapy with the compact single-room MEVION-S250 proton therapy system

Simulation study of proton arc therapy with the compact single-room MEVION-S250 proton therapy system

Out-of-field doses for scanning proton radiotherapy of shallowly located paediatric tumours—a comparison of range shifter and 3D printed compensator

The European radiation dosimetry group – Review of recent scientific achievements

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