Measurement of Skin Surface Acidity

Darlenski, Razvigor; Fluhr, Joachim W.

doi:10.1007/978-3-319-26594-0_12-1

Cited by 1 publication

(1 citation statement)

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“…Close to the skin surface, it slightly increases again [7]. Even on healthy skin, the surface pH is quite variable between individuals and ranges from 4 to 6 [8, 9]. Generally, the skin pH can be measured precisely and reliably in vivo and non‐invasively with a flat glass electrode [10].…”

Section: Introductionmentioning

confidence: 99%

Investigating the effect of the pH of foot care product formulations on pedal skin in diabetic and non‐diabetic subjects

Fitzner

Knuhr²,

Brandt³

et al. 2023

Intern J of Cosmetic Sci

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Objective: The use of skin care formulations with acidic pHs is seen as an effective method to maintain the acidic mantel of the skin; however, because the skin pH varies depending on the area of the body and as data are lacking for the skin pH of the feet, there was a need to examine whether this assumption holds true for skin care formulations designed for the foot. Thus, three foot creams formulated with a neutral, acidic or alkaline pH were compared with each other as well as to an untreated control group in order to analyse their impact on skin pH, hydration and general skin condition.Methods: An exploratory clinical investigation with 60 enrolled subjects, half of whom had a diagnosis of diabetes (type 1 or type 2), was undertaken. The investigation followed a randomized, double-blind, balanced incomplete block design (BIBD) including intra-individual comparison (before and after treatment).Evaluations of skin pH and hydration were carried out using a pH meter and a Corneometer respectively. Objective evaluation of skin condition for efficacy assessment was performed by a trained grader. For tolerability evaluation, objective and subjective dermatological assessments were performed.Results: At the end of the treatment period, the skin pH was largely unchanged at five out of six of the test areas, with the mean value for each treatment group using test products showing similar fluctuations as the untreated control group. Furthermore, the skin condition parameters studied all improved by a comparable magnitude for each of the treatment groups using the test products, whereas the untreated control group experienced a worsening of the skin condition parameters. Conclusions:The results of this investigation suggest that where the skin of the foot is concerned, the pH of skin care formulations has no (physiologically) relevant influence on the skin's pH in either diabetic or non-diabetic subjects.Furthermore, the expectation that acidic formulations would be more beneficial for the skin's condition was not found to hold true for the skin of the foot, as noThis is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Section: Introductionmentioning

confidence: 99%