Measurement of R1 dynamics using sliding window‐DESPOT

Schulz, Jessica; Korn, Matthias; Woenne, Eva C.; Umathum, Reiner; Briel, Andreas; Hengerer, Arne; Semmler, Willi; Bock, Michael

doi:10.1002/jmri.21946

Cited by 2 publications

(1 citation statement)

References 29 publications

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“…The choice of an optimal T1 quantification method depends on spatial and temporal resolution required to measure T1 as accurately and reliably as possible and many imaging strategies for this purpose were previously developed for intravenously (IV) injected contrast in studies of tumors and stroke (25,26). Some of these methods including the windows method (27), two flip angle method (28,29) and 3D EPI look-locker method (30) were developed specifically for DCE-MRI applications with IV injection of contrast. In the case of the glymphatic system, CSF solute (contrast) transport is much slower (min) compared to IV contrast injection studies (sec) and therefore a 3D VFA-SPGR approach is suitable.…”

Section: Discussionmentioning

confidence: 99%

Quantitative Gd‐DOTA uptake from cerebrospinal fluid into rat brain using 3D VFA‐SPGR at 9.4T

Lee

Mortensen

Sanggaard

et al. 2017

Magnetic Resonance in Med

114

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Imaging strategies for accurate 3D contrast concentration mapping at 9.4T were developed and whole brain dynamic concentration maps were derived to study solute transport via the glymphatic system. The newly developed approach will enable future quantitative studies of the glymphatic system in health and disease states. Magn Reson Med 79:1568-1578, 2018. © 2017 International Society for Magnetic Resonance in Medicine.

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