Measurement of Power Consumption in Stirred Vessels—A Review

Ascanio, Gabriel; Castro, B.; Galindo, Enrique

doi:10.1205/cerd.82.9.1282.44164

Cited by 116 publications

(56 citation statements)

References 21 publications

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“…The power input into the medium can be determined experimentally by a number of techniques [13], all of which are difficult to apply accurately at the very small scale of the 10 ambr. Here, power measurement was performed on a specially-built stand-alone ambr bioreactor vessel as used in the workstation.…”

Section: Computational Fluid Dynamics Cfdmentioning

confidence: 99%

The physical characterisation of a microscale parallel bioreactor platform with an industrial CHO cell line expressing an IgG4

Nienow

Rielly

Brosnan

et al. 2013

Biochemical Engineering Journal

113

106

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Section: Computational Fluid Dynamics Cfdmentioning

confidence: 99%

The physical characterisation of a microscale parallel bioreactor platform with an industrial CHO cell line expressing an IgG4

Nienow

Rielly

Brosnan

et al. 2013

Biochemical Engineering Journal

113

106

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“…The stirrers were attached to a viscometer Haake VT 550 to measure the torque and rotational frequency. This procedure is recommended in the literature for small-scale vessels [25]. It allows the determination of the torque with an accuracy of ± 100 lNm.…”

Section: Measurement Proceduresmentioning

confidence: 99%

Flow Field Analysis of Stirred Liquid‐Liquid Systems in Slim Reactors

Maaß¹,

Eppinger²,

Altwasser³

et al. 2011

Chem Eng & Technol

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Previous studies have shown the great potential, but also the great challenges, in handling slim reactors often used for polymerization reactions. Experiments and simulations were carried out in reactors with aspect-to-diameter ratios of up to 5, to test and to evaluate the mixing and dispersion efficiency for liquid-liquid systems of single-and multiple-stage impellers. Therefore, power consumption, mixing time and minimum dispersion speed were determined for five different stirrer types under turbulent conditions. It was found that the dimensionless mixing time is highly sensitive to the configuration of the impellers, with almost no dependency on the turbulent power number. Another focus was the analysis of the effect of the baffles. The influence of the baffle length in slim reactors on the mixing time and the macroscopic flow field was determined.

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“…The power consumption depends on many factors, among others on the operating parameters of a process and physical parameters of a fluid, as well as the amount of gas supplied to the system. The impact of various parameters on power consumption has been the subject of much research (Adamiak, 2005;Adamiak and Karcz, 2007;Ascanio et al, 2004;Gill et al, 2008;Kamieński, 2004;Karcz and Siciarz, 2001;Markopoulos and Panntuflas, 2001;Nienow and Lilly, 1996;Roman and Tudose, 1997;Stręk, 1981;Vilaca et al, 2000;Yianatos, 2010). Typically adding gas phase to a liquid causes a decrease in power consumption as compared with results achieved for liquid phase alone.…”

Section: Introductionmentioning

confidence: 99%

Hydrodynamic Characteristics of Mechanically Agitated Air - Aqueous Sucrose Solutions

Cudak

2014

Chemical and Process Engineering

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The aim of the research presented in this paper was determination of power consumption and gas hold-up in mechanically agitated aerated aqueous low concentration sucrose solutions. Experimental studies were conducted in a vessel of diameter 0.634 m equipped with high-speed impellers (Rushton turbine, Smith turbine or A 315). The following operating parameters were changed: volumetric gas flow rate (expressed by superficial gas velocity), impeller speed, sucrose concentration and type of impeller. Based on the experiments results, impellers with a modified shape of blades, e.g. CD 6 or A 315, could be recommended for such gas-liquid systems. Power consumption was measured using strain gauge method. The results of gas holdup measurements have been approximated by an empirical relationship containing dimensionless numbers (Eq. (2)).

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Measurement of Power Consumption in Stirred Vessels—A Review

Cited by 116 publications

References 21 publications

The physical characterisation of a microscale parallel bioreactor platform with an industrial CHO cell line expressing an IgG4

The physical characterisation of a microscale parallel bioreactor platform with an industrial CHO cell line expressing an IgG4

Flow Field Analysis of Stirred Liquid‐Liquid Systems in Slim Reactors

Hydrodynamic Characteristics of Mechanically Agitated Air - Aqueous Sucrose Solutions

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