Measurement of oxygen concentration for detection of subclinical mastitis

Wittek, Thomas; Mader, C; Ribitsch, V; Burgstaller, Johann

doi:10.17236/sat00228

Cited by 5 publications

(3 citation statements)

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“…33 Notably, the dissolved oxygen level in milk dips during IMI as oxygen is consumed by the increased somatic cell population in IMI milk. 34 Bacteria and their byproducts trigger macrophages to release chemo-attractants that recruit polymorphonuclear neutrophils (PMNs) to the site of invasion to provide the second line of innate immune protection. 35 The intracellular granules of PMNs contain several bactericidal peptides, such as defensins, and neutral and acidic proteases (such as elastase, cathepsin, and procathepsin) that can inhibit a variety of mastitis pathogens.…”

Section: Risk Factors Associated With Bovine Mastitismentioning

confidence: 99%

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Bovine Mastitis: Examining Factors Contributing to Treatment Failure and Prospects of Nano-enabled Antibacterial Combination Therapy

Majumder

Eckersall

George

2023

ACS Agric. Sci. Technol.

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Bovine mastitis, primarily caused by microbial infections of cow mammary glands leading to inflammation, is the costliest disease in the dairy industry. The severity and the responsiveness of mastitis to treatment depend on the dynamic interplay between the host, pathogen, and environmental factors. Evidently, the prospects of managing mastitis with conventional antibiotic treatment and disease management strategies are grim with the emergence of antimicrobial resistance (AMR) and the prevalence of virulence characteristics such as biofilm formation and intracellular survival among the persistent pathogens. Thus, there is a need for safe and economically viable alternate therapies capable of targeting broad-spectrum pathogens displaying AMR and virulence characteristics. Recent progress in the application of nanotechnology in drug delivery and infection control provides unprecedented opportunities for resolving recalcitrant infections. While the advantages of nanotechnology have been exploited for therapeutic delivery in humans, the potential of nanotechnology is yet to be realized in animal agriculture, especially for treating bovine mastitis. This review provides an overview of risk factors and pathogenesis associated with bovine mastitis that challenge the success of current treatment strategies and highlights how those unique challenges could be exploited for designing effective nano-enabled antibacterial combination therapy for bovine mastitis treatment.

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Section: Risk Factors Associated With Bovine Mastitismentioning

confidence: 99%

“…This, however, could increase to >400,000/mL depending on the stage and severity of IMI . Notably, the dissolved oxygen level in milk dips during IMI as oxygen is consumed by the increased somatic cell population in IMI milk …”

Section: Risk Factors Associated With Bovine Mastitismentioning

confidence: 99%

Bovine Mastitis: Examining Factors Contributing to Treatment Failure and Prospects of Nano-enabled Antibacterial Combination Therapy

Majumder

Eckersall

George

2023

ACS Agric. Sci. Technol.

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“…With the advancement of diagnostic methods for somatic cell count (SCC), as well as its ability to diagnose mastitis rapidly and efficiently, SCC has been incorporated into the Dairy Herd Improvement (DHI) program [23]. At present, the number of somatic cells in milk has been proven to be an important parameter for the diagnosis of mastitis, especially for the diagnosis of subclinical mastitis [24]. However, the SCC diagnostic method also has some shortcomings.…”

Section: Introductionmentioning

confidence: 99%

A Study on Differential Biomarkers in the Milk of Holstein Cows with Different Somatic Cells Count Levels

She

Liu

et al. 2023

Animals

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Dairy cow mastitis is one of the common diseases of dairy cows, which will not only endanger the health of dairy cows but also affect the quality of milk. Dairy cow mastitis is an inflammatory reaction caused by pathogenic microorganisms and physical and chemical factors in dairy cow mammary glands. The number of SCC in the milk of dairy cows with different degrees of mastitis will increase in varying degrees. The rapid diagnosis of dairy cow mastitis is of great significance for dairy cow health and farm economy. Based on the results of many studies on the relationship between mastitis and somatic cell count in dairy cows, microflora, and metabolites in the milk of Holstein cows with low somatic cell level (SCC less than 200,000), medium somatic cell level (SCC up to 200,000 but less than 500,000) and high somatic cell level (SCC up to 5000,00) were analyzed by microbiome and metabolic group techniques. The results showed that there were significant differences in milk microbiota and metabolites among the three groups (p < 0.05), and there was a significant correlation between microbiota and metabolites. Meanwhile, in this experiment, 75 differential metabolites were identified in the H group and L group, 40 differential metabolites were identified in the M group and L group, and six differential microorganisms with LDA scores more than four were found in the H group and L group. These differential metabolites and differential microorganisms may become new biomarkers for the diagnosis, prevention, and treatment of cow mastitis in the future.

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Sensitive screen-printed electrodes with the colorimetric zone for simultaneous determination of mastitis and ketosis in bovine milk samples

Thiruvengadam

Venkidasamy

Selvaraj

et al. 2020

Journal of Photochemistry and Photobiology B: Biology

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Measurement of oxygen concentration for detection of subclinical mastitis

Cited by 5 publications

References 0 publications

Bovine Mastitis: Examining Factors Contributing to Treatment Failure and Prospects of Nano-enabled Antibacterial Combination Therapy

Bovine Mastitis: Examining Factors Contributing to Treatment Failure and Prospects of Nano-enabled Antibacterial Combination Therapy

A Study on Differential Biomarkers in the Milk of Holstein Cows with Different Somatic Cells Count Levels

Sensitive screen-printed electrodes with the colorimetric zone for simultaneous determination of mastitis and ketosis in bovine milk samples

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