Measurement of overall perceived health using different scales in patients with rheumatoid arthritis: a proposal of a combined scale

Díaz, Eybar; Cajas, Javier; Casallas, Alex; Abella, Jorge; Morales, Renán; Rondón, Federico; Quintana, Gerardo; Iglesias, Antonio; Medina, Yimy F.

doi:10.1016/j.rcreue.2020.06.007

Cited by 1 publication

(3 citation statements)

References 27 publications

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“…It is endorsed by the American College of Rheumatology and the European League Against Rheumatism for clinical trials [ 13 , 14 ]. The instrument was initially designed for comparing clinical trial outcomes of RA treatments, although these indices are now also used as overall markers of disease activity in daily clinical practice [ 15 – 19 ].…”

Section: Discussionmentioning

confidence: 99%

“…SDAI has been extensively validated and has shown high sensitivity and specificity for predicting how physicians will modify therapy. Both indices are well-known and widely used in research and in clinical settings [ 10 , 12 – 15 , 19 ].…”

Section: Discussionmentioning

confidence: 99%

“…Disease activity measures such as the 28-joint Disease Activity Score (DAS28), the Simplified Disease Activity Index (SDAI), and the Clinical Disease Activity Index (CDAI) cover the most relevant aspects of RA in a single score [ 12 – 15 ]. DAS28 is used in clinical trials and routine monitoring to evaluate response to treatment and inform decisions on the need to begin or adjust treatment [ 12 – 19 ].…”

Section: Introductionmentioning

confidence: 99%

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Development of a novel clinimetric tool: PAtient Reported Disease Activity Index in Rheumatoid Arthritis (PARDAI-RA) by PANLAR, for the assessment of patients living with rheumatoid arthritis

Fernández-Ávila,

Patiño-Hernández,

Moreno-Luna

et al. 2024

Clin Rheumatol

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Background Clinical experience has shown that a single measure is not sufficient to assess disease activity in rheumatoid arthritis (RA). Various clinimetric tools are necessary to address the many clinical situations that can arise. Methods In order to develop a comprehensive measurement tool, the Pan American League of Associations for Rheumatology searched for the most frequent measures of disease activity applied in RA by means of a semi-systematic review of the available literature. Results We found that the most frequently reported measures of disease activity were the 28-joint Disease Activity Score, C-reactive protein, and the erythrocyte sedimentation rate, followed by patient-reported measures of pain and stiffness and many other composite indices and patient-reported outcome measures. The most frequent physician-reported sign of disease was the swollen joint count, and the most frequently self-reported feature was the increase in disease activity or flares. Conclusion In this article, we present a new clinimetric tool developed based on expert consensus and on data retrieved from our search. Disease activity can be better assessed by combining various data sources, such as clinical, laboratory, and self-reported outcomes. These variables were included in our novel clinimetric tool. Key Points• The goal of treatment of RA is to achieve the best possible control of inflammation, or even remission; therefore, disease management should include systematic and regular evaluation of inflammation and health status.• Clinimetric tools evaluate a series of variables (e.g., symptoms, functional capacity, disease severity, quality of life, disease progression) and can reveal substantial prognostic and therapeutic differences between patients.• Our clinimetric tool, which is based on a combination of data (e.g., clinical variables, laboratory results, PROMs), can play a relevant role in patient assessment and care.

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