Measurement of macular thickness with optical coherence tomography: impact of using a paediatric reference database and analysis of interocular symmetry

Muñoz-Gallego, A.; Torres-Peña, José L.; Rodríguez‐Salgado, Martín; Ortueta‐Olartecoechea, Ana; López-López, Cristina; Cruz, Javier de la; Tejada-Palacios, P.

doi:10.1007/s00417-020-04903-5

Cited by 2 publications

(1 citation statement)

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“…No currently marketed OCT devices have reference values for patients aged <18 years, thus limiting its application in children. [ 3 ]…”

Section: Introductionmentioning

confidence: 99%

Optic disc morphology and interocular symmetry in children

Muñoz-Gallego,

Rodríguez-Salgado,

López-López

et al. 2024

Saudi Journal of Ophthalmology

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PURPOSE: The purpose of the study was to obtain a pediatric reference database for optic disc parameters and interocular symmetry. To ascertain factors that modify these parameters (age, spherical equivalent [SE], and sex). METHODS: This was a cross-sectional study. 90 patients aged 5–17 years fulfilled all the inclusion criteria. After a full examination including cycloplegic refraction, all patients underwent optical coherence tomography (OCT) of the papilla using the three-dimensional (3D) scan protocol of the Topcon 3D 2000 OCT device. We provide reference values for optic disc parameters in the pediatric population. We also retrieved interocular symmetry reference values for these parameters. RESULTS: The multivariate regression analysis did not reveal variations in any of the optic disc parameters associated with age, sex, or SE (all P ≥ 0.126). The 95th percentile limit for absolute interocular differences for the cup-to-disc area ratio was 0.24. The multivariate regression analysis revealed the absence of a correlation between asymmetry of the optic disc parameters and age, sex, and the interocular difference in SE (all P ≥ 0.105). CONCLUSION: Pediatric reference databases for optic disc parameters and ranges of normality for interocular symmetry provide key diagnostic support in diseases that affect the optic nerve.

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“…No currently marketed OCT devices have reference values for patients aged <18 years, thus limiting its application in children. [ 3 ]…”

Section: Introductionmentioning

confidence: 99%