Measurement of Liver Stiffness with 2D-Shear Wave Elastography (2D-SWE) in Bariatric Surgery Candidates Reveals Acceptable Diagnostic Yield Compared to Liver Biopsy

Jamialahmadi, Tannaz; Nematy, Mohsen; Jangjoo, Ali; Goshayeshi, Ladan; Rezvani, Reza; Ghaffarzadegan, Kamran; Nooghabi, Mehdi Jabbari; Shalchian, Payman; Zangui, Mahtab; Javid, Zeinab; Doaei, Saeid; Rajabzadeh, Farnood

doi:10.1007/s11695-019-03889-2

Cited by 37 publications

(32 citation statements)

References 40 publications

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“…Regarding quantification of steatosis severity, we considered CAP as a reference method using the cut-off values proposed by Eddowes et al 2019 [30], although published studies have failed to establish uniformly accepted cut-off values for CAP in differentiating between steatosis grades [8,9,36]. In our study, we observed a very good correlation of ATI from Canon with CAP: r=0.81, p<0.0001.…”

Section: Discussionsupporting

confidence: 56%

“…Thus, noninvasive methods are necessary for the assessment of liver fibrosis and steatosis. Several methods -Transient Elastography (TE), point Shear Wave Elastography (pSWE) and Two-Dimensional Shear Wave Elastography (2D-SWE) [5][6][7][8][9] -are used for the assessment of liver fibrosis in such patients. The Controlled Attenuation Parameter (CAP), implemented on the FibroScan device (Echosens, Paris, France) was firstly used for the noninvasive assessment of steatosis severity and has shown a correlation with histologic grades in adults [10][11][12].…”

Section: Introductionmentioning

confidence: 99%

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Quantification of Steatosis and Fibrosis using a new system implemented in an ultrasound machine

et al. 2020

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Aim: The study compared the usefulness of 2D-SWE and attenuation measurements obtained using Aplio i800 from Canon together with Transient Elastography (TE) and the Controlled Attenuation Parameter (CAP) as the reference method.Material and methods: We included 112 consecutive adults with reliable LS measurements, 44 healthy subjects and 68 subjects with chronic hepatopathies in whom liver stiffness (LS) and steatosis were evaluated in the same session employing two elastography techniques: Transient Elastography (TE) with Controlled Attenuation Parameter (CAP) implemented on the FibroScan® 530 Compact system and Two Dimensional Shear Wave Elastography (2D-SWE) with Attenuation Imaging (ATI) installed on the Aplio i800 series ultrasound system. Reliable measurements were defined as the median value of 10, respectively 5 valid LS measurements for TE and 2D-SWE, with an interquartile range interval/median ratio (IQR/M) <30%.Results: A very strong positive correlation was found between LS values obtained by TE and 2D-SWE: r=0.88, p<0.0001 and between the attenuation coefficients of steatosis obtained by CAP and ATI, r=0.81, p<0.0001. The best cut-off values by 2DSWE for predicting different stages of liver fibrosis were: for F≥2 - 7.9 kPa and F=4 - 11.7 kPa. Regarding steatosis, the best ATI cut-off values were: for S≥1 - 0.79 dB/cm/mHz and for S3 - 0.86 dB/cm/mHz.Conclusion: 2D-SWE and ATI measurements with the new system strongly correlated with TE and CAP results.

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Section: Discussionsupporting

confidence: 56%

Section: Introductionmentioning

confidence: 99%

Quantification of Steatosis and Fibrosis using a new system implemented in an ultrasound machine

et al. 2020

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“…B. 2-D-Schwerwellenelastografie) zutrifft [10], jedoch müssen diese Verfahren noch intensiver bei NAFLD evaluiert werden.…”

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Stellenwert der transienten Elastografie zur Risikobewertung bei NAFLD

2019

Gastroenterologie up2date

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“…Indeed, the presence of NAFLD-related cirrhosis is predominantly more conducive to liver-related complications, i.e., hepatic decompensation (ascites or upper gastrointestinal bleeding secondary to portal hypertension or hepatic encephalopathy) or HCC, whereas the presence of histological "bridging" liver fibrosis is more closely associated with an increased risk of developing major vascular events (myocardial infarction, heart failure requiring hospitalization, angina, aneurysm dissection, cardiac arrest, and ischemic or hemorrhagic stroke) and extrahepatic cancers [3]. Of the three key histological elementary lesions of NAFLD/NASH [1], the amount of liver fat content (LFC) and the severity of liver fibrosis can be accurately assessed with several noninvasive imaging techniques, including magnetic resonance imaging-based proton density fat fraction (MRI-PDFF) and shear wave elastography (SWE), respectively [4,5].…”

mentioning

confidence: 99%

“…Among the major strengths of this cross-sectional study is that patients were recruited at a single university center on Chinese individuals with NAFLD who were consecutively observed over a 4-year period. LFC was measured with MRI-PDFF and liver stiffness with 2D-SW which are deemed to be accurate imaging techniques for diagnosing and staging liver steatosis and fibrosis [4,5]. Nevertheless, the study lacks an adequate group of control individuals without NAFLD and its cross-sectional design limits establishing temporality or causality of the observed associations.…”

mentioning

confidence: 99%