Measurement of lamina and prelaminar thicknesses of both eyes in patients with unilateral branch retinal vein occlusion

Son, Yengwoo; Lee, Seung-Woo; Park, Jongyeop

doi:10.1007/s00417-016-3491-y

Cited by 11 publications

(11 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our findings were consistent with previous findings, which indicated that there are similarities in the changes in the parapapillary area and ONH between patients with BRVO and glaucoma. [3][4][5][6][7][8] The finding of significant thinning of the mean PCT in the eyes with focal LC defects in both the BRVO and glaucoma groups supports the hypothesis that vascular insufficiency is, to some extent, involved in the pathophysiology of these two diseases. The short posterior ciliary artery (SPCA) supplies blood to the posterior choriocapillaries, from the macular to the equator and the peripapillary areas.…”

Section: Plos Onesupporting

confidence: 61%

“…If both BRVO and glaucoma share a common pathophysiologic change that affects the parapapillary area and the ONH, the findings of previous studies can also be explained more easily. [3][4][5][6][7][8] However, further prospective studies are needed to determine the specific pathophysiologic mechanism associated with peripapillary choroidal change and focal LC defects in patients with BRVO.…”

Section: Plos Onementioning

confidence: 99%

“…[5] Subsequent studies have further investigated changes in the optic nerve head (ONH) region, especially the lamina cribrosa (LC), in patients with BRVO. [6,7] These studies found that significant reductions in LC thickness occur in the eyes of patients with BRVO. One study used optical coherence tomography angiography (OCTA) to evaluate changes in peripapillary microvasculature parameters in the fellow eyes of the patients with unilateral RVO.…”

Section: Introductionmentioning

confidence: 99%

“…Taken together, these study results indicate that the changes in the peripapillary choroid and ONH are similar between patients with BRVO and patients with glaucoma. [3][4][5][6][7][8] Thus, our hypothesis was that BRVO and glaucoma may share a common pathophysiology that results in these similarities.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Focal lamina cribrosa defects and significant peripapillary choroidal thinning in patients with unilateral branch retinal vein occlusion

et al. 2020

View full text Add to dashboard Cite

To investigate the prevalence of focal lamina cribrosa (LC) defects in patients with unilateral branch retinal vein occlusion (BRVO) and to compare ocular characteristics between eyes with and without focal LC defect and those eyes with normal-tension glaucoma (NTG). Methods This retrospective, cross-sectional study included 121 patients. Thirty-nine patients had unilateral BRVO (BRVO group), 36 patients had NTG (NTG group), and 36 patients had vitreous floaters, but no other ocular diseases (control group). In addition to baseline characteristics such as age, sex, refractive errors, the ocular characteristics such as peripapillary choroidal thickness (PCT), retinal nerve fiber layer thickness, and subfoveal choroidal thickness were retrospectively analyzed. Results Focal LC defects were detected in 20 eyes of 14 patients (38.9%) in the BRVO group, 24 eyes of 15 patients (41.7%) in the NTG group, and none in the control group (P<0.001). In the BRVO-affected eyes, the mean PCT was 102.7±31.1 μm in the eyes with focal LC defects, and 163.1±70.1 μm in the eyes without LC defects (P = 0.009). In the BRVOaffected eyes, the mean PCT was 102.7±31.1 μm in the eyes with focal LC defects, and 163.1±70.1 μm in the eyes without LC defects (P = 0.009). In the NTG group, the mean PCT was 133.1±48.9 μm in the eyes with focal LC defects and 170.8±81.9 μm in those without (P = 0.042). The other baseline and ocular characteristics were not significantly different between the eyes with and without focal LC defects in both the BRVO group and the NTG group.

show abstract

Section: Plos Onesupporting

confidence: 61%

Section: Plos Onementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Focal lamina cribrosa defects and significant peripapillary choroidal thinning in patients with unilateral branch retinal vein occlusion

et al. 2020

View full text Add to dashboard Cite

show abstract

“…For this reason, it is pivotal that LC morphology is normal. In previous studies, the LC was identified as the primary site of optic-nerve damage in glaucoma [18,19], and defects in the structure were proposed to be associated with the development of RVO [11,20]. Although researchers have also demonstrated the association between glaucoma and RVO, the underlying pathogenesis that these conditions have in common remains unclear [4,21].…”

Section: Discussionmentioning

confidence: 99%

Thickness of the Lamina Cribrosa, Retinal-Nerve Fiber Layer, and Peripapillary Choroid in Patients with Branch Retinal Vein Occlusion

Sırakaya

Küçük

2019

Ophthalmologica

View full text Add to dashboard Cite

To compare the thickness of the lamina cribrosa (LC), retinal-nerve fiber layer (RNFL), and peripapillary choroid (PC) in patients with unilateral branch retinal-vein occlusion (BRVO) and healthy individuals. Methods: The 70 eyes of 35 patients with unilateral BRVO, grouped as either affected or unaffected, and 38 right eyes of 38 healthy individuals were examined for LC, RNFL, PC thickness, and LC depth with spectral-domain optical coherence tomography. Results: The unaffected eyes of patients with BRVO had a significantly thinner RNFL on average and in the inferior quadrant than the eyes of healthy controls. Mean LC thickness in BRVO-affected and BRVO-unaffected eyes was significantly thinner than in controls, and mean LC depth was significantly deeper as well. The average, superior, and inferior PC thickness in both BRVO-affected and BRVO-unaffected eyes and nasal PC thickness in the BRVO-affected eyes were significantly thinner than in the eyes of controls. Conclusion: Thinner LCs and PCs in both eyes of patients with unilateral BRVO and thinner RNFLs in BRVO-unaffected eyes than in the eyes of healthy controls suggest that BRVO and glaucoma have underlying pathological mechanisms and risk factors in common that lead to their development.

show abstract

Reply

Kang

Choi

Koh

et al. 2018

Retina

View full text Add to dashboard Cite

Measurement of lamina and prelaminar thicknesses of both eyes in patients with unilateral branch retinal vein occlusion

Cited by 11 publications

References 32 publications

Focal lamina cribrosa defects and significant peripapillary choroidal thinning in patients with unilateral branch retinal vein occlusion

Focal lamina cribrosa defects and significant peripapillary choroidal thinning in patients with unilateral branch retinal vein occlusion

Thickness of the Lamina Cribrosa, Retinal-Nerve Fiber Layer, and Peripapillary Choroid in Patients with Branch Retinal Vein Occlusion

Reply

Contact Info

Product

Resources

About