Measurement of Functional Residual Capacity During Mechanical Ventilation for Acute Respiratory Failure

Hylkema, Bs; Barkmeijerdegenhart, P; Mark, T W van der; Peset, R; Sluiter, Hj

doi:10.1378/chest.81.1.27

Cited by 13 publications

(5 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Its accuracy was assessed by scanning large reservoirs containing a soapy emulsion obtained from known volumes of water, soap, and air. To date, FRC has been measured mainly in ARDS by nitrogen [28] or sulfur hexafluoride washout [9,29] and open and closed circuit helium dilution techniques [28,30]. These methods have the advantage of being noninvasive and thus allowing repeated bedside measurements.…”

Section: Methodological Considerationsmentioning

confidence: 99%

Regional distribution of gas and tissue in acute respiratory distress syndrome. I. Consequences for lung morphology

Puybasset

Cluzel²,

Gusman³

et al. 2000

Intensive Care Med

265

222

View full text Add to dashboard Cite

show abstract

Section: Methodological Considerationsmentioning

confidence: 99%

Regional distribution of gas and tissue in acute respiratory distress syndrome. I. Consequences for lung morphology

Puybasset

Cluzel²,

Gusman³

et al. 2000

Intensive Care Med

265

222

View full text Add to dashboard Cite

show abstract

“…AM Loss of aerated lung volume is a characteristic feature of acute lung injury (ALI) and is commonly observed after major thoracic and abdominal surgical procedures. Reduction in lung volume is generally assessed by measuring FRC, using gas dilution techniques such as nitrogen (1) or sulfur hexafluoride (2,3) washout and open-and closed-circuit helium dilution techniques (1,4). These methods have the advantage of being noninvasive, allowing bedside and repeated measurements.…”

mentioning

confidence: 99%

“…These methods have the advantage of being noninvasive, allowing bedside and repeated measurements. However, they are not always reproducible (1,2,5) and do not provide any measurement of the volume of nonaerated lung. Furthermore, there are some important limitations common to all these techniques when applied to patients with ALI: ( 1 ) the diseased lung is characterized by the presence of poorly aerated areas where the gas mixing is problematic, ( 2 ) distention of previously aerated regions cannot be distinguished from true alveolar recruitment when FRC increases after positive end-expiratory pressure (PEEP), and ( 3 ) regional distribution of aerated and nonaerated lung volumes and of PEEPinduced alveolar recruitment cannot be assessed.…”

mentioning

confidence: 99%

A Computed Tomography Scan Assessment of Regional Lung Volume in Acute Lung Injury

Puybasset

Cluzel²,

Nan³

et al. 1998

Am J Respir Crit Care Med

243

146

View full text Add to dashboard Cite

The lobar and cephalocaudal distribution of aerated and nonaerated lung and of PEEP-induced alveolar recruitment is unknown in acute lung injury (ALI). Dimensions of the lungs and volumes of aerated and nonaerated parts of each pulmonary lobe were measured using a computerized tomographic quantitative analysis and compared between 21 patients with ALI and 10 healthy volunteers. Distribution of PEEP-induced alveolar recruitment along the anteroposterior and cephalocaudal axis and influence of the resting volume of nonaerated lower lobes were also assessed. Anteroposterior and transverse dimensions of the lungs of the patients were similar to those of healthy volunteers, whereas cephalocaudal dimensions were reduced by more than 15%. Total lung volume (aerated plus nonaerated lung) was reduced by 27%. Volumes of upper and lower lobes were 99 and 48% of normal values. In addition to an anteroposterior gradient in the distribution of aerated and nonaerated areas, a cephalocaudal gradient was also observed. Nonaerated areas were predominantly found in juxtadiaphragmatic regions. PEEP-induced alveolar recruitment was more pronounced in nondependent than in dependent regions and in cephalad than in caudal regions. A significant correlation between resting volume of nonaerated lower lobes and regional PEEP-induced alveolar recruitment was observed. In ALI, loss of lung volume involves predominantly lower lobes. The thorax shortens along its cephalocaudal axis. PEEP-induced alveolar recruitment predominates in nondependent and cephalad lung regions and is inversely correlated with the resting volume of nonaerated lung.

show abstract

“…Dilution techniques give lower values than plethysmography and cannot be performed without modification of ventilator or the breathing circuit. In addition, during measurement with the dilution technique the breathing pattern is substantially changed and a negative pressure has to be applied [10,22]. Respiratory inductive plethysmography can only be used to measure the change of the FRC values [13].…”

Section: Discussionmentioning

confidence: 99%

Measurement of functional residual capacity by nitrogen washout during partial ventilatory support

et al. 2003

View full text Add to dashboard Cite

show abstract

Measurement of Functional Residual Capacity During Mechanical Ventilation for Acute Respiratory Failure

Cited by 13 publications

References 8 publications

Regional distribution of gas and tissue in acute respiratory distress syndrome. I. Consequences for lung morphology

Regional distribution of gas and tissue in acute respiratory distress syndrome. I. Consequences for lung morphology

A Computed Tomography Scan Assessment of Regional Lung Volume in Acute Lung Injury

Measurement of functional residual capacity by nitrogen washout during partial ventilatory support

Contact Info

Product

Resources

About