“…13 Therefore, it is imperative to construct an analytical method to estimate ClO − in complicated biological and environmental systems selectively and sensitively. To date, many analytical techniques were used to quantify ClO − such as potentiometry, 14 ion-chromatography, 15 colorimetry, 16,17 chemiluminescence, 18 and fluorometry. 19 Despite the advantages of the colorimetric and fluorometric-based strategies for the detection of analytes, but they depend on a single-mode (rely solely on one quantitative technique), which influenced by environmental factors and non-standard assay procedures, affecting the reliability of the quantitation especially in complex matrices.…”