2015
DOI: 10.1053/j.gastro.2015.01.026
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Measurement of Fecal Calprotectin Improves Monitoring and Detection of Recurrence of Crohn's Disease After Surgery

Abstract: and PV Desmond have no conflicts of interest to declare. P De Cruz has received travel grant support from Abbott and Schering-Plough. MA Kamm has acted as an advisor to Abbott and Janssen, has received research support from Abbott, and has acted as a speaker at symposiums sponsored by Abbott and Janssen. A Hamilton has received an educational grant from Abbott. D Liew has served on advisory boards and received research grants from Abbott. IC Lawrance has been on an advisory board for Abbott and Janssen, a spea… Show more

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Cited by 241 publications
(183 citation statements)
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“…FC was a relatively accurate predictor of both endoscopic and histological disease recurrence with AUROC values of 0.71 and 0.78. Even though this is a retrospective study based on a small sample, our results strongly suggest postoperative FC behaves in children and adolescents similarly as previously demonstrated among adult CD patients [8,25]. Fasting, bowel preparation, and requirement of anesthesia make endoscopies particularly demanding for children.…”
Section: Discussionsupporting
confidence: 76%
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“…FC was a relatively accurate predictor of both endoscopic and histological disease recurrence with AUROC values of 0.71 and 0.78. Even though this is a retrospective study based on a small sample, our results strongly suggest postoperative FC behaves in children and adolescents similarly as previously demonstrated among adult CD patients [8,25]. Fasting, bowel preparation, and requirement of anesthesia make endoscopies particularly demanding for children.…”
Section: Discussionsupporting
confidence: 76%
“…Ileum is affected in 70% of children and is prone to stricture and fistula formation, which occur in about 25% of pediatric CD patients [3,4,6]. Resection of the affected bowel segment either because of such complications or for unresponsive luminal disease is performed in 30-50% of pediatric CD patients by young adulthood [4,7] and as many as 70% of operated patients require further surgery during their lifetime [8,9].…”
mentioning
confidence: 99%
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