Measurement of dental caries experience‐modification of the DMFT index

Anaise, Joseph Z.

doi:10.1111/j.1600-0528.1984.tb01408.x

Cited by 54 publications

(38 citation statements)

References 4 publications

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“…Two boys of caries-active (DMFT ≧ 6) patients of DMFT equals to 7 and 9 were taken into this study. Moreover, two healthy individuals of one boy and one girl with DMFT of 0 were included in this study as healthy controls.“Healthy” individuals (DMFT = 0) and “caries-active (DMFT ≧ 6)” subjects (DMFT ≧ 6) were defined based on DMFT index, which measures the number of decayed, missing and filled teeth in epidemiologic surveys of dental caries (Anaise 1984). All reported no antibiotics intake for the preceding at least 6 months and no smoking or tobacco used.…”

Section: Methodsmentioning

confidence: 99%

Characterization of saliva microbiota’s functional feature based on metagenomic sequencing

et al. 2016

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Objective Saliva, a mixture of exocrinally secretive fluids, amounts to ~1.5 L daily and harbors numerous microbial inhabitants. However, except the organismal structure of saliva microbiota, the functional profile of saliva microbiota remain elusive.MethodsHere we used metagenomic sequencing to experimentally reconstruct the global genomic profile of saliva by sequencing total saliva DNA from two healthy and two caries-active (DMFT ≧ 6) adults.ResultsWe found that saliva microbiota, representing 30–60% of total saliva DNA in our samples, might carry functional signatures that were site-specific and caries-state-specific. Among microbiota from different hosts, a prominent functional core, but not an organismal core, was identified. Each microbiota exhibited functional redundancy where dominant genomes tend to encode more functional diversity yet without necessarily contributing to dominant functions. Furthermore, genetic polymorphisms of hosts were also unraveled from salivary DNA without apparent physical or sequence bias in human chromosomes.ConclusionsThe microbial functional sensitivity to disease, links to specific functions, and permission of simultaneous genotyping of hosts and microbiota suggested sequencing salivary DNA might be an advantageous venue in uncovering both human and microbial basis of oral infections.Electronic supplementary materialThe online version of this article (doi:10.1186/s40064-016-3728-6) contains supplementary material, which is available to authorized users.

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Section: Methodsmentioning

confidence: 99%

Characterization of saliva microbiota’s functional feature based on metagenomic sequencing

et al. 2016

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“…The DMFT index measures the number of decayed, missing and filled teeth in epidemiologic surveys of dental caries (Anaise, 1984). It was adopted in our study to measure each individual's caries status and thus to define and distinguish the caries-active subjects and healthy subjects.…”

Section: Methodsmentioning

confidence: 99%

Saliva microbiomes distinguish caries-active from healthy human populations

et al. 2011

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The etiology of dental caries remains elusive because of our limited understanding of the complex oral microbiomes. The current methodologies have been limited by insufficient depth and breadth of microbial sampling, paucity of data for diseased hosts particularly at the population level, inconsistency of sampled sites and the inability to distinguish the underlying microbial factors. By cross-validating 16S rRNA gene amplicon-based and whole-genome-based deep-sequencing technologies, we report the most in-depth, comprehensive and collaborated view to date of the adult saliva microbiomes in pilot populations of 19 caries-active and 26 healthy human hosts. We found that: first, saliva microbiomes in human population were featured by a vast phylogenetic diversity yet a minimal organismal core; second, caries microbiomes were significantly more variable in community structure whereas the healthy ones were relatively conserved; third, abundance changes of certain taxa such as overabundance of Prevotella Genus distinguished caries microbiota from healthy ones, and furthermore, caries-active and normal individuals carried different arrays of Prevotella species; and finally, no 'caries-specific' operational taxonomic units (OTUs) were detected, yet 147 OTUs were 'caries associated', that is, differentially distributed yet present in both healthy and caries-active populations. These findings underscored the necessity of species-and strain-level resolution for caries prognosis, and were consistent with the ecological hypothesis where the shifts in community structure, instead of the presence or absence of particular groups of microbes, underlie the cariogenesis.

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“…In contrast, the DMFS index is based on the number of carious, missing, and filled tooth surfaces. Both indices have been used for more than 50 years and are well established as key measures of caries experience in dental epidemiology [11]. …”

Section: Introductionmentioning

confidence: 99%

Associations of Community Water Fluoridation with Caries Prevalence and Oral Health Inequality in Children

Kim

et al. 2017

IJERPH

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This study aimed to confirm the association between the community water fluoridation (CWF) programme and dental caries prevention on permanent teeth, comparing to a control area, neighbouring population without the programme, and verifying whether the programme can reduce the socio-economic inequality related to the oral health of children in Korea. Evaluation surveys were conducted among 6-, 8-, and 11-year-old children living in Okcheon (CWF) and neighbouring Yeongdong (non-CWF, control area) towns in South Korea. Data on monthly family income, caregiver educational level, and Family Affluence Scale scores were evaluated using questionnaires that were distributed to the parents. The effectiveness of CWF in caries reduction was calculated based on the differences in decayed, missing, and filled teeth and decayed, missing, and filled tooth surfaces indices between the two towns. The data were analysed using logistic regression and univariate analysis of variance. Both 8- and 11-year-old children living in the CWF area had lower dental caries prevalence than those living in the non-CWF community. Differences in dental caries prevalence based on educational level were found in the control area but not in the CWF area. Socio-economic factor-related inequality in oral health were observed in the non-CWF community. Additionally, 8- and 11-year-old children living in the CWF area displayed lower dental caries prevalence in the pit-and-fissure and smooth surfaces than those living in the non-CWF community. These results suggest that CWF programmes are effective in the prevention of caries on permanent teeth and can reduce oral health inequalities among children. The implementation of CWF programmes should be sustained to overcome oral health inequalities due to socio-economic factors and improve children’s overall oral health.

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Measurement of dental caries experience‐modification of the DMFT index

Cited by 54 publications

References 4 publications

Characterization of saliva microbiota’s functional feature based on metagenomic sequencing

Characterization of saliva microbiota’s functional feature based on metagenomic sequencing

Saliva microbiomes distinguish caries-active from healthy human populations

Associations of Community Water Fluoridation with Caries Prevalence and Oral Health Inequality in Children

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