Measurement of Creatinine in Peritoneal Dialysis Fluid

Farrell, S C; Bailey, M. P.

doi:10.1177/000456329102800616

Cited by 24 publications

(17 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[12] Briefly, 2 μl of sample was added to 240 μl of working reagent and the mixture was incubated at room temperature for 30 min to measure the absorbance at 505 nm. 20 μl of 30% acetic acid was added to the wells and further incubated for 10 min.…”

Section: Methodsmentioning

confidence: 99%

Renoprotective effect of aged garlic extract in streptozotocin- induced diabetic rats

2013

View full text Add to dashboard Cite

Objective:Aged garlic extract (AGE) has been proven to exhibit antioxidant, hypolipidemic, hypoglycemic and antidiabetic properties. However, its effect on diabetic nephropathy was unexplored. Therefore, the present study was designed to investigate the renoprotective effect of AGE in streptozotocin-induced diabetic rats.Materials and Methods:Albino Wistar rats were induced with diabetes by a single intraperitoneal injection of 45 mg/kg b.w. of streptozotocin. Commercially available AGE was supplemented orally at a dose of 500 mg/kg body weight/day. Aminoguanidine, which has been proven to be an anti-glycation agent was used as positive control and was supplemented at a dose of 1 g/L in drinking water. The serum and urinary biochemical parameters were analyzed in all the groups and at the end of 12 weeks follow up, the renal histological examination were performed using H & E and PAS staining.Results:The diabetic rats showed a significant change in the urine (P < 0.001) and serum (P < 0.01) constituents such as albumin, creatinine, urea nitrogen and glycated hemoglobin. In addition, the serum lipid profile of the diabetic rats were altered significantly (P < 0.05) compared to that of the control rats. However, the diabetic rats supplemented with aged garlic extract restored all these biochemical changes. The efficacy of the extract was substantiated by the histopathological changes in the kidney.Conclusion:From our results, we conclude that aged garlic extract has the ability to ameliorate kidney damage in diabetic rats and the renoprotective effect of AGE may be attributed to its anti-glycation and hypolipidemic activities.

show abstract

Section: Methodsmentioning

confidence: 99%

Renoprotective effect of aged garlic extract in streptozotocin- induced diabetic rats

2013

View full text Add to dashboard Cite

show abstract

“…The creatinine concentrations in dialysate were corrected for glucose concentration [8]. Estimated body surface area (BSA) was calculated based on height, weight, and sex of the patient using the du Bois formula [9].…”

Section: Methodsmentioning

confidence: 99%

Delivered Dialysis Dose with PD Plus Therapy

Díaz-Buxó

Youngblood²,

Torres³

1998

Am J Nephrol

View full text Add to dashboard Cite

Aim: To evaluate the effect of PD Plus on weekly Kt/V_urea and creatinine clearance (K_cr) among patients undergoing CAPD/CCPD (continuous ambulatory peritoneal dialysis/continuous cyclic peritoneal dialysis). Methods: The kinetic studies of 92 CAPD and 18 CCPD patients who transferred to PD Plus were analyzed. All patients underwent CAPD/CCPD and PD Plus for a minimum of 3 months. Standard collection methods were used and kinetic indices calculated with the Pack PD Kinetic Modeling program. 57 patients had transport data and were modeled for a target weekly Kt/V_urea ≥2.1 using PD Plus with ≤15 liters dialysate/day. 6 patients were supervised during the collection periods by research nurses. The actual results for all patients (110) and for the supervised patients were compared against the modeled results. Results:45% of the patients achieved a Kt/V_urea ≥2.1 and 47% a K_cr ≥60 liters/1.73 m² with PD Plus, but only 20% did so with CAPD/CCPD. A close correlation between the supervised patients and modeled therapy was observed. Conclusions: Adequate dialysis is possible by using higher fill volumes, the supine position, and optimal dwell times (PD Plus) in most patients. The discrepancy between modeled and achieved dose is likely due to poor compliance with therapy, inadequate training, or poor specimen collection.

show abstract

“…7 The unknown effect of fluid matrix interferences in the assays used in the studies makes it challenging to rely on published data for result interpretation. Many current laboratory creatinine assays are Jaffe-based, which continue to suffer from interference by high glucose.…”

Section: General Correspondencementioning

confidence: 99%

Global call to arms for physicians and clinical laboratories: harmonised approach to non‐serum body fluid testing

Choy

2018

Internal Medicine Journal

View full text Add to dashboard Cite

Measurement of Creatinine in Peritoneal Dialysis Fluid

Abstract: The peritoneal equilibration test (PET) is a standardized procedure to assess peritoneal membrane performance in patients on continuous ambulatory 2 Cook JGH. Factors influencing the assay of creatinine.

Cited by 24 publications

References 1 publication

Renoprotective effect of aged garlic extract in streptozotocin- induced diabetic rats

Renoprotective effect of aged garlic extract in streptozotocin- induced diabetic rats

Delivered Dialysis Dose with PD Plus Therapy

Global call to arms for physicians and clinical laboratories: harmonised approach to non‐serum body fluid testing

Contact Info

Product

Resources

About