Measurement of covalent bond formation in light-curing hydrogels predicts physical stability under flow
Jonathan M. Zatorski,
Isabella L. Lee,
Jennifer E. Ortiz-Cárdenas
et al.
Abstract:Photocrosslinking hydrogels are promising for tissue engineering and regenerative medicine, but challenges in reaction monitoring often leave their optimization subject to trial and error. The stability of crosslinked gels under fluid flow, as in the case of a microfluidic device, is particularly challenging to predict, both because of obstacles inherent to solid-state macromolecular analysis that prevent accurate chemical monitoring, and because stability is dependent on size of the patterned features. To sol… Show more
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