Measles, mumps, and rubella: A cross-sectional study of susceptibility to vaccine-preventable diseases among young people in India

Karade, Santosh; Sen, Sourav; Sashindran, V K; Sharma, Punita; Kanitkar, Madhuri

doi:10.1016/j.mjafi.2018.12.010

Cited by 7 publications

(5 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although the measles, mumps and rubella vaccine has been administered more commonly in recent years in India, it is still not included in the routine vaccination program. 26 When evaluating anti-rubella Total cost (TRY † ) 400 563.28 †TRY: New Turkish Lira. ; ‡SOGC: The Society of Obstetricians and Gynaecologists of Canada.…”

Section: Discussionmentioning

confidence: 99%

“…We considered the rubella immunization programs of various countries, accessibility of healthcare services and hygienic conditions to be the most important factors for this low anti‐rubella IgM positivity rate. Although the measles, mumps and rubella vaccine has been administered more commonly in recent years in India, it is still not included in the routine vaccination program . When evaluating anti‐rubella IgG results, however, the seroprevalence positivity rate was found to be 95.27% (9293/9754).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Impact of Syrian refugees on congenital TORCH infections screening in Turkey

Çoşkun

Gülümser²,

Çoşkun

et al. 2020

J of Obstet and Gynaecol

View full text Add to dashboard Cite

Aim: To demonstrate the effect of the Syrian refugee population on the prevalence of congenital TORCH (Toxoplasmosis, Other [syphilis, parvovirus B19], Rubella, Cytomegalovirus [CMV] and Herpes) infections and to evaluate the cost-effectiveness of population-based TORCH screening during pregnancy in Turkey. Methods: Pregnant women (n = 9754) were enrolled. Ultrasonographic findings, immunoglobulin (Ig)M and IgG seropositivity, avidity, amniocentesis and DNA-polymerase chain reaction (PCR) results were compared. Costs were calculated based on invoice amounts from the Health Applications Communique pricing system. Results: The prevalence of TORCH seropositivity in Turkey was not significantly different between all regions (P > 0.05). Overall, 1333 (13.67%) pregnant Syrian refugees were included in the study. Acute CMV, rubella and Toxoplasma gondii infections (according to low IgG avidity in IgM positive patients) were detected in 17.82%, 21.53% and 14.07% of women, respectively. Twenty-four women underwent an amniocentesis procedure and nine of them had positive DNA-PCR and reverse transcription-PCR results. All women with positive results opted to terminate the pregnancy. There was no statistical difference among groups according to the rate of low IgG avidity in IgM-positive patients and termination rates for T. gondii, rubella and CMV (P > 0.05). Total cost for screening the entire study population was presented in US dollars (USD). A total of 71 529 and prenatal diagnosis with positive invasive test results were obtained in nine women: toxoplasmosis in four, CMV in three and rubella in two women. Conclusion: Population-based screening for prenatal TORCH infections is not cost-effective in Turkey. Syrian refugees have a limited effect on the increasing prevalence of congenital TORCH infections.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Impact of Syrian refugees on congenital TORCH infections screening in Turkey

Çoşkun

Gülümser²,

Çoşkun

et al. 2020

J of Obstet and Gynaecol

View full text Add to dashboard Cite

show abstract

“…Migrant workers who participated in the survey on latent tuberculosis and provided consent for their data and residual sera to be used for future research were eligible for inclusion in our study. For this serological study, the minimum sample size for each country of origin and birth cohort was determined based on published reports of measles seroprevalence in Bangladesh [ 13 ], China [ 14 ], India [ 15 ] and Malaysia [ 16 ] (Additional file 1 : Table S1) with a confidence level of 95% and relative precision of 5%. For migrant workers from Indonesia, Myanmar and the Philippines, we assumed their measles antibody prevalence was at least 85% in each birth cohort, which gave a minimum sample size of 272 with a confidence level of 95% and relative precision of 5%.…”

Section: Methodsmentioning

confidence: 99%

Prevalence of measles antibodies among migrant workers in Singapore: a serological study to identify susceptible population subgroups

et al. 2022

View full text Add to dashboard Cite

Background In 2019, two clusters of measles cases were reported in migrant worker dormitories in Singapore. We conducted a seroprevalence study to measure the level of susceptibility to measles among migrant workers in Singapore. Methods Our study involved residual sera of migrant workers from seven Asian countries (Bangladesh, China, India, Indonesia, Malaysia, Myanmar and the Philippines) who had participated in a survey between 2016 and 2019. Immunoglobulin G (IgG) antibody levels were first measured using a commercial enzyme-linked immunosorbent assay (ELISA) test kit. Those with equivocal or negative IgG results were further evaluated using plaque reduction neutralization test (PRNT). Results A total of 2234 migrant workers aged 20–49 years were included in the study. The overall prevalence of measles IgG antibodies among migrant workers from the seven Asian countries was 90.5% (95% confidence interval 89.2–91.6%). The country-specific seroprevalence ranged from 80.3 to 94.0%. The seroprevalence was significantly higher among migrant workers born in 1965–1989 than those born in 1990–1999 (95.3% vs. 86.6%, p < 0.0005), whereas there was no significant difference by gender (90.8% in men vs. 89.9% in women, p = 0.508). 195 out of 213 samples with equivocal or negative ELISA results were tested positive using PRNT. Conclusion The IgG seroprevalence in migrant workers was below the herd immunity threshold of 95% for measles. Sporadic outbreaks may occur in susceptible individuals due to high transmissibility of measles virus. Seroprevalence surveys can help identify susceptible subgroups for vaccination.

show abstract

“…10 In recent years, many measles outbreaks have been reported among adolescents and adults. [11][12][13] A review article from the Indian subcontinent revealed the changing trend in the endemicity of hepatitis A infection, with more susceptible adolescents/ adults than previously observed. Older age groups were reported to present with more severe symptoms of hepatitis A.…”

mentioning

confidence: 99%