Mean Platelet Volume in Patients with Chronic Venous Insufficiency

Sarıca, Mehmet Akif; Kızıldağ, Betül; Selçuk, Mustafa Yavuz; Tutak, Ayse Sahin; Baykan, Ali Haydar; Bulut, Hacı Taner; Türkbeyler, İbrahim Halil

doi:10.5799/jcei.328685

Cited by 2 publications

(2 citation statements)

References 13 publications

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“…Hypertension, heart failure, peripheral arterial disease, chronic obstructive pulmonary disease, diabetes mellitus, and skeletal system or joint diseases are some of the prevalent comorbidities associated with CVD [30]. In the Beebe-Dimmer et al's study, hypertension was considered as a risk factor for VV and CVI, but more studies are needed [31].…”

Section: Discussionmentioning

confidence: 99%

Risk factors for chronic venous insufficiency in nurses in Türkiye - NueVo TR

Akay,

Yavas,

Uguz

et al. 2024

Turk J Vasc Surg

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Aim: Chronic venous insufficiency (CVI) is a condition that results from obstruction, valve insufficiency, dysfunction of calf muscle pump, or their combinations. This study analyzed the risk factors and demographic characteristics of CVI in nurses in Türkiye. Additionally, it seeks to identify the total number of patients treated at medical centers in 2022 and assess the prevalence of CVI. Material and Methods: This multicenter, descriptive, and cross-sectional study was conducted with the participation of nurses working in 18 centers. Nurses completed a questionnaire that included their demographic information and venous insufficiency risk factors, and the Venous Insufficiency Epidemiological and Economic Study-Quality of Life Questionnaire. Researchers also completed the Standard CEAP Form Section C. The cases were divided into 2 groups: CVI (-) group (n=776, 43.5%) and CVI (+) group (n=1010, 56.5%). Results: A total of 1786 nurses participated in this study. Older age (>30-39 years), female gender, ≥2 pregnancies, ≥2 childbirths, years in the profession (>5-15 years), family history, and night cramps were identified as risk factors for CVI (p<0.001). No significant difference was found between smoking, body mass index, and CVI status (p>0.05). Hypertension, diabetes, and a history of deep vein thrombosis were the most common coexisting diseases. With a one-unit increase in age, risk of CVI increased 1.1-fold, family history of VV increased CVI risk 1.9-fold and presence of nocturnal night cramps increased risk of CVI 2.6-fold. The prevalence of CVI in 2022 was found to be 22.66% in this study. Conclusion: Older age, female gender, ≥2 pregnancies, ≥2 childbirths, years in the profession, family history, and night cramps are identified as risk factors for CVI in nurses. Common comorbid diseases include hypertension, diabetes, and a history of DVT. Pregnancy, particularly with multiple occurrences, stands out as a critical period for CVI. Reported symptoms in CVI (+) nurses include leg pain, swelling, heaviness, restless legs, and throbbing. Nurses demonstrate a higher incidence of CVI compared to other professions, highlighting an occupational risk. These findings stress the importance of preventive measures for nurses.

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Section: Discussionmentioning

confidence: 99%

Risk factors for chronic venous insufficiency in nurses in Türkiye - NueVo TR

Akay,

Yavas,

Uguz

et al. 2024

Turk J Vasc Surg

View full text Add to dashboard Cite

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“…16 In patients with CVI, MPV has also been studied in a few reports in the literature. In a case-control study, Sarıca et al 17 investigated the importance of MPV in patients with CVI and whether MPV was likely to be a predictor of CVI. The authors found that the mean MPV value was significantly higher in patients diagnosed with CVI compared to healthy individuals and concluded that MPV could be utilized as a follow-up marker in patients with CVI.…”

Section: Discussionmentioning

confidence: 99%

Platelet distribution width in young patients with chronic venous insufficiency

et al. 2021

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Objective Platelet distribution width (PDW) has been reported in a wide range of pathological settings. In this study, we aimed to investigate the relationship between PDW and lower extremity chronic venous insufficiency (CVI) by comparing the levels of PDW and other parameters derived from complete blood count (CBC) tests in young individuals with or without lower extremity CVI. Methods This prospective clinical study was conducted between January 2020 and December 2020. A total of 108 patients, 72 patients with lower extremity CVI (study group) and 36 healthy volunteers (control group) were enrolled from the Bursa Yuksek Ihtısas Educatıon Research Hospıtal and the Bolu Abant Izzet Baysal University Training and Research Hospital. The age range of the participants was between 18 and 50 years old. Participants’ baseline clinical features and CBC parameters including PDW, white blood cell, hemoglobin, hematocrit, mean corpuscular volume, red cell distribution width, neutrophil, lymphocyte, platelet count, mean platelet volume, plateletcrit, neutrophil-to-lymphocyte ratio, and platelet-to-lymphocyte ratio were compared between the two groups. Results The groups were statistically similar in terms of baseline clinical features. The median PDW value was significantly higher for the CVI patients relative to the control group (17.6 vs 16.8; p < 0.001). In terms of other CBC parameters, there were no significant differences between the groups. According to ROC analysis, area under the curve of PDW was 0.749 (95% confidence interval: 0.653–0.846 and p < 0.001). If the value of PDW was accepted as 17, it could predict CVI with 76% sensitivity and 59% specificity, whereas a PDW value of 17.5 could predict CVI with 51% sensitivity and 81% specificity. Conclusion Platelet distribution width might be a useful marker to determine an increased inflammatory response and thrombotic status in young patients with CVI.

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Mean Platelet Volume in Patients with Chronic Venous Insufficiency

Cited by 2 publications

References 13 publications

Risk factors for chronic venous insufficiency in nurses in Türkiye - NueVo TR

Risk factors for chronic venous insufficiency in nurses in Türkiye - NueVo TR

Platelet distribution width in young patients with chronic venous insufficiency

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