Mean platelet volume and its prognostic value in acute coronary syndrome complicated by cardiogenic shock

Supel, Karolina; Salska, Agata; Jaskiewicz, Filip; Kacprzak, Michał; Zielińska, Marzenna

doi:10.5603/cj.2013.0070

Cited by 6 publications

(5 citation statements)

References 26 publications

(33 reference statements)

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“…Mean MPV was 11.51±1.61 which was significant (p=0.0001). These observations were similar compared to the study carried out by Supel K et al 18 We evaluated the prognostic value of MPV in AMI complicated by cardiogenic shock. Such an analysis in patients with the most serious and fatal complication of ACS has not been performed so far.…”

Section: Discussionsupporting

confidence: 80%

Mean platelet volume as a predictor of clinical outcomes in patients of acute myocardial infarction

2019

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Background: High levels of mean platelet volume (MPV), as an indicator of larger, more reactive platelets resulting from an increased platelet turnover, may represent a risk factor for overall vascular mortality and other cardiovascular events, including myocardial infarction (MI). The present study was undertaken to see the predictive value of MPV in accessing the clinical outcomes in acute myocardial infarction, (AMI).Methods: Total consecutive 114 cases of AMI admitted to intensive care unit were enrolled in the study and were compared with the equal number of age and gender-matched controls. The clinical evaluation of cases was done at admission and on day 7 in terms of a) Cardiogenic shock, b) Arrhythmia and c) Effect of thrombolysis. Patients were classified according to tertile of baseline MPV.Results: The mean age of cases was 55.56±12.19 years. Males (66.67%) were outnumbering females (33.33%) in cases and controls showing male to female ratio of 2:1. Mean MPV was 10.2±1.27fl in cases and 7.26±0.79fl in controls which was statistically significant. Correlation of MPV with cardiogenic shock, arrhythmia and mortality was significant. Correlation of MPV with risk factor shows that diabetes was the only risk factor significant in AMI. Multiple logistic regression of risk factors with mortality in AMI shows that high MPV and obesity was found to be independently associated with mortality in AMI.Conclusions: Mean platelet volume is simple, easily available and cheap method. Serial estimation of MPV is a predictor of adverse clinical outcome in AMI so treating doctor can be more vigilant.

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Section: Discussionsupporting

confidence: 80%

Mean platelet volume as a predictor of clinical outcomes in patients of acute myocardial infarction

2019

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“…One of these comorbid conditions was diabetes mellitus. Supel et al (2013) also reported that blood glucose level and cardiogenic shock were significantly associated; it can be seen from P-Value < 0.001. Tekbas also reported that other parameters like the white blood cell and platelet number, creatinine level, and left ventricle function were significantly associated with death in ACS patients.…”

Section: Resultsmentioning

confidence: 84%

“…Tekbas also reported that other parameters like the white blood cell and platelet number, creatinine level, and left ventricle function were significantly associated with death in ACS patients. Furthermore, Cuenca et al (2012) also reported that the MPV value might predict the occurrence of death in ACS patients within six months; it can be seen from P-Value < 0.05 (P-Value: 0.018) [19], [20].…”

Section: Resultsmentioning

confidence: 98%

Association between Mean Platelet Volume (MPV) and Mayor Cardiovascular Incidence among Inpatient Acute Myocardial Infraction with ST-Elevation

A.S.Hutabarat¹,

Hasan²,

Akbar³

2022

IJHP

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MPV value is an index of platelet associated with platelet activity. A larger platelet size shows a hyper-reactive platelet and accelerates thrombus formation with coronary circulation, leading to major cardiovascular events. Hence, this study was designed to investigate the relationship between MPV value and each type of major cardiovascular event in General Hospital Haji Adam Malik. This study was observational research with a cross-sectional design in General Hospital Haji Adam Malik in October 2014-January 2015 among sixty-nine ACS inpatients with ST-Elevation. The evaluated major cardiovascular events were death, heart failure, arrhythmia, and cardiogenic shock. The average MPV value of ACS patients with heart failure, cardiogenic shock, arrhythmia, death, and all major cardiovascular events was 10.08 fL, 10.40 fL, 10.00 fL, 9.76 fL, and 10.00 fL, respectively. Either major cardiovascular event did not show any significant difference in the average MPV value due to these P-Values > 0.05. Hence, it can be concluded that the MPV value cannot be used to predict the incidence of either major cardiovascular event in ACS patients.

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“…Lökosit alt gruplarının ve oranlarının AKS'da prognostik değeri olabileceği öne sürülmüştür (19,20) . NLO'nun primer PCI sonrası kardiyovasküler komplikasyonları ön gör-mede bağımsız bir prediktör olduğu gösterilmiştir (21,22) . NLO devam eden non-spesifi k infl amasyonun iki bağımsız gösterge-sidir (23) .…”

Section: Discussionunclassified

Relationship Between Admission Neutrophil to Lymphocyte Ratio and ST-Elevation Myocardial İnfarction Complicated by Cardiogenic Shock

Alızade¹,

Çerşit²,

Bulut³

et al. 2016

Kosuyolu Heart Journal

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ÖZETGiriş: Nötrofi l-lenfosit oranı (NLO) akut koroner sendromların fi zyopatolojisi ile ilişkilidir. ST segment elevasyonlu miyokart infarktüsünde (STEMİ) gözlenen infl amatuvar süreç NLO'da artışa sebep olabilir. Çalış-mamızda, STEMİ ile hastaneye başvuran hastalarda kardiyojenik şok (KŞ) gelişen ve gelişmeyen gruplar arasında NLO'da fark olup olmadığı araştırıldı. Hastalar ve Yöntem:Çalışmaya akut STEMİ ile başvuran toplam 203 hasta alındı. Yüz hasta KŞ grubunu oluşturdu. Yüz üç hastada ise komplikasyonsuz STEMİ mevcuttu. Tüm hastalardan rutin kan örnekleri alındı. NLO analizi yapıldı.Bulgular: NLO gruplar arasında anlamlı olarak farklı bulundu (9.9 ± 7.9 vs. 6.2 ± 4.3, sırasıyla, p< 0.001). "Multiple logistic regression" analizi, KŞ'yle komplike STEMİ'nin şok izlenmeyen STEMİ hasta grubuna göre daha yüksek NLO değerlerine sahip olduğunu gösterdi (β= 1.07, %95 CI 1.01-1.15, p= 0.03).Sonuç: Çalışmamızda hastaneye başvuruda ölçülen NLO'nun KŞ gelişen STEMİ hastalarında anlamlı olarak daha yüksek olduğu bulundu. Artmış NLO oranı KŞ gelişecek hastaları predikte etmede kullanılabilir.Anahtar Kelimeler: Nötrofi l/lenfosit oranı; karsinojenik şok; ST segment elevasyonlu miyokart infarktüsü; infl amasyon; ateroskleroz Relationship Between Admission Neutrophil to Lymphocyte Ratio and ST-Elevation Myocardial İnfarction Complicated by Cardiogenic ShockABSTRACT Introduction: Neutrophil to lymphocyte ratio (NLR) is related to the pathogenesis of acute coronary syndromes. The infl ammatory process in ST-elevation myocardial infarction (STEMI) may cause an increase in NLR. In this study, we aimed to investigate whether admission NLR is associated with STEMI complicated by cardiogenic shock. Patients and Methods:The study population comprised patients who had presented with acute STEMI. All patients referred underwent routine blood tests, including common blood cell counts, and NLR analysis.Results: STEMI showed characteristics of cardiogenic shock in 100 patients and was uncomplicated in 103 patients. NLR was signifi cantly different between the two groups (9.9 ± 7.9 vs. 6.2 ± 4.3, respectively, p< 0.001). Multiple logistic regression analyses showed that NLR was signifi cantly associated with STEMI complicated by cardiogenic shock (β= 1.07, 95% CI 1.01-1.15, p= 0.03). Conclusion:Our results demonstrated that admission NLR was higher in patients with STEMI complicated by cardiogenic shock. To prove this relationship between NLR and cardiogenic shock, further investigations are needed.

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Mean platelet volume and its prognostic value in acute coronary syndrome complicated by cardiogenic shock

Abstract: (Cardiol J 2013; 20, 3: 254-260)

Cited by 6 publications

References 26 publications

Mean platelet volume as a predictor of clinical outcomes in patients of acute myocardial infarction

Mean platelet volume as a predictor of clinical outcomes in patients of acute myocardial infarction

Association between Mean Platelet Volume (MPV) and Mayor Cardiovascular Incidence among Inpatient Acute Myocardial Infraction with ST-Elevation

Relationship Between Admission Neutrophil to Lymphocyte Ratio and ST-Elevation Myocardial İnfarction Complicated by Cardiogenic Shock

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