Mean age and gender distribution of patients with major mental disorders participating in clinical trials

Bandelow, Borwin; Schüller, Katharina

doi:10.1007/s00406-018-0972-5

Cited by 13 publications

(8 citation statements)

References 7 publications

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“…Looking first at income, demographic data, and lifestyle variables, we found that women reported anxiety more frequently than men. This is consistent with the literature, which has shown women to be twice as likely to suffer from anxiety disorders as men and that this distribution is stable across cultures (Bandelow and Schüller, 2020 ; Bandelow and Michaelis, 2022 ). There are biological [e.g., Bandelow and Domschke ( 2015 )], psychosocial [e.g., Bandelow et al ( 2002 )], and societal [e.g., Hurrelmann and Kolip ( 2015 )] explanations for this.…”

Section: Discussionsupporting

confidence: 92%

My home—my castle? Self-reported anxiety varies in relation to the subjective evaluation of home environment

Weber,

Mascherek,

Augustin

et al. 2024

Front. Psychol.

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IntroductionAlthough people spend most of the day in their home environment, the focus of research in environmental psychology to date has been on factors outside the home. However, it stands to reason that indoor quality likewise has an impact on psychological well-being. Therefore, the present study addresses the question of whether the subjective evaluation of home environmental parameters are related to self-reported anxiety and whether they can additionally explain variance beyond the usual sociodemographic and general lifestyle variables.MethodsData from the Hamburg City Health Study (first 10,000 participants) was analyzed. A subsample of N = 8,886 with available GAD-7 anxiety data was selected, and hierarchical regression models were computed, with demographic data entered first, followed by variables concerning lifestyle/habits and finally variables of the subjective evaluation of home environment.ResultsUsing the integrated model, we were able to explain about 13% of the variance in self-reported anxiety scores. This included both the demographic, lifestyle, and subjective evaluation of home environment variables. Protection from disturbing night lights, a greater sense of security, less disturbing noises, brighter accommodations, and a satisfactory window view explained almost 6% of the variance and was significantly associated with lower anxiety scores.ConclusionThe home as a place of refuge plays an increasingly important role as home office hours rise. It is therefore crucial to identify domestic factors contributing to people's mental well-being. The subjective evaluation of one's home environment has proven influential over and above modifiable lifestyle variables.

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Section: Discussionsupporting

confidence: 92%

My home—my castle? Self-reported anxiety varies in relation to the subjective evaluation of home environment

Weber,

Mascherek,

Augustin

et al. 2024

Front. Psychol.

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“…Unfortunately, the gap between needing help and seeking help is substantial. Only one in three young people seek help for their mental health problems ( 19 , 20 ), and most individuals present to services at a much later stage ( 21 – 23 ). Subsequently these individuals present with more developed and severe problems that are more difficult to treat, and have more functional and social consequences since the mental illness strikes in a critical developmental period where social, vocational and educational milestones were to be achieved ( 15 , 24 ).…”

Section: Introductionmentioning

confidence: 99%

Online Indicated Preventive Mental Health Interventions for Youth: A Scoping Review

et al. 2021

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Objective: Between the ages of 12 and 25 the onset of mental disorders typically occurs, and the burden of mental health problems is greatest for this group. Indicated preventive interventions to target individuals with subclinical symptoms to prevent the transition to clinical levels of disorders have gained considerable traction. However, the threshold to seek help appears to be high even when help is needed. Online interventions could offer a solution, especially during the COVID-19 pandemic. This scoping review will present an overview of the recent research of indicated online preventive interventions for youth (12–25 years) experiencing the early stages of mental health complaints with the aim of identifying the nature and extent of the research evidence.Methods: The 5-stage framework by Arksey and O'Malley was used. Academic literature published from 2013 onwards in printed or electronic format was included from Scopus, PsychINFO, and Ovid MEDLINE(R) ALL.Results: The search yielded 11,122 results, with the final selection resulting in inclusion of 30 articles for this review. In total, the articles included 4,950 participants. 26.7% of the selected articles focused on youth between 12 and 25 years. Of the articles 60% did not screen for, nor exclude participants with clinical levels of symptoms. Most studies used a common evidence-based therapy for the disorder-category targeted. More than half of the online interventions included some form of human support. Adherence levels ranged between 27.9 and 98%. The results indicate general effectiveness, usability and acceptability of online indicated preventive interventions. The most commonly used approach was CBT (n = 12 studies). Studies varied in their size, rigor of study, effectiveness and outcome measures. Online interventions with a combination of clinical and peer moderation (n = 3 studies) appear to result in the most stable and highest effect sizes.Conclusion: Online indicated preventive mental health interventions for youth with emerging mental health issues show promise in reducing various mental health complaints, and increasing positive mental health indicators such as well-being and resilience. Additionally, high levels of usability and acceptability were found. However, the included studies show important methodological shortcomings. Also, the research has mainly focused on specific diagnostic categories, meaning there is a lack of transdiagnostic approaches. Finally, clear definitions of- as well as instruments to measure- emerging or subclinical mental health symptoms in youth remain are missing.

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“…We compared the age of the participants in the studies with a database on the average age of participants in 832 clinical studies [ 13 ]. The mean age (PDA: 38.6, GAD 38.2; SAD 35.7) in the evaluated studies was similar to the typical age of participants calculated in this database (PDA: 37.2, GAD 40.7; SAD 35.2).…”

Section: Resultsmentioning

confidence: 99%

Internet psychotherapeutic interventions for anxiety disorders – a critical evaluation

Bandelow¹,

Wedekind²

2022

BMC Psychiatry

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Background During the COVID-19 pandemic, internet-delivered psychotherapeutic interventions (IPI) move increasingly into the focus of attention. Method We reviewed 39 randomized controlled studies of IPIs with 97 study arms (n = 4122 patients) for anxiety disorders (panic disorder/agoraphobia, generalized anxiety disorder, and social anxiety disorder) and performed a meta-analysis. Most studies were conducted with cognitive behavioural approaches (iCBT). Results were compared with a previous meta-analysis examining medications and face-to-face (F2F) psychotherapy. Results In direct comparisons, IPIs were as effective as F2F-CBT and superior to waitlist controls. Programs with more intensive therapist contact yielded higher effect sizes (ES). We compared the obtained ES with a previous comprehensive meta-analysis of 234 studies. In this comparison, iCBT was less effective than individual F2F-CBT and medications, not different from pill placebos, and more effective than psychological placebo and waitlist (p > .0001 for all comparisons). ES of IPIs may be overestimated. Treatments were only compared to waitlist, which is not a sufficient control condition. 97% of the studies were not blinded with regard to the main outcome measure. 32% of the participants received antianxiety drugs during the trials. In 89%, participants were recruited by advertisements rather than from clinical settings, and 63% of the participants had an academic background (students or university employees) which might affect the generalizability of the findings. Remote diagnoses were often made by students without completed training in psychotherapy. In only 15% of the studies, diagnoses were made in personal contact with a psychiatrist or psychologist. In 44% of the studies, the ‘therapists’ maintaining remote contact with the participants were mostly students without completed psychotherapy education. Conclusions IPIs may be a useful tool when face-to-face psychotherapy is not easily available, or as an add-on to standard psychotherapeutic or psychopharmacological treatments but should perhaps not be used as monotherapy. We have suggested standards for future research and the practical use of IPIs.

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Mean age and gender distribution of patients with major mental disorders participating in clinical trials

Cited by 13 publications

References 7 publications

My home—my castle? Self-reported anxiety varies in relation to the subjective evaluation of home environment

My home—my castle? Self-reported anxiety varies in relation to the subjective evaluation of home environment

Online Indicated Preventive Mental Health Interventions for Youth: A Scoping Review

Internet psychotherapeutic interventions for anxiety disorders – a critical evaluation

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