MDRANet: A multiscale dense residual attention network for magnetic resonance and nuclear medicine image fusion

Fu, Jun; Li, Weisheng; Peng, Xiuxiu; Du, Jiao; Ouyang, Aijia; Wang, Qian; Chen, Xin

doi:10.1016/j.bspc.2022.104382

Cited by 11 publications

(1 citation statement)

References 55 publications

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“…With the rapid development of nuclear magnetic resonance (NMR) technology, it is used in many fields. − Compared with high-field NMR, low-field NMR has the advantages of small size, simple operation, low cost, and high precision. − NMR technology generally achieves rapid detection by altering the aggregation or dispersion states of magnetic particles. In the field of biology, this technique is used to detect various targets such as RNA, viruses, harmful compounds, and so forth.…”

Section: Introductionmentioning

confidence: 99%

NMR Immunosensor Based on a Targeted Gadolinium Nanoprobe for Detecting Salmonella in Milk

Guo,

Yi,

et al. 2024

Anal. Chem.

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Detecting harmful pathogens in food is not only a crucial aspect of food quality management but also an effective way to ensure public health. In this paper, a complete nuclear magnetic resonance biosensor based on a novel gadolinium (Gd)-targeting molecular probe was developed for the detection of Salmonella in milk. First, streptavidin was conjugated to the activated macromolecular polyaspartic acid (PASP) via an amide reaction to generate SA−PASP. Subsequently, the strong chelating and adsorption properties of PASP toward the lanthanide metal gadolinium ions were exploited to generate the magnetic complex (SA− PASP−Gd). Finally, the magnetic complex was linked to biotinylated antibodies to obtain the bioprobe and achieve the capture of Salmonella. Under optimal experimental conditions, the sensor we have constructed can achieve a rapid detection of Salmonella within 1.5 h, with a detection limit of 7.1 × 10 3 cfu mL −1 .

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